Distribution of genetic variance in gynogenetic or androgenetic families

Bongers, A.B.J.; Bovenhuis, H.; Stokkom, A.C. van; Wiegertjes, G.F.; Zandieh-Doulabi, Behrouz; Komen, J.; Richter, C.J.J.

doi:10.1016/s0044-8486(97)00027-6

Cited by 23 publications

(10 citation statements)

References 20 publications

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“…In the present case each family was reared separately and this may have also had a confounding effect with the additive genetic effect and may have inflated the heritability estimates. The estimated heritability values obtained in our study are similar to other studies conducted in food fishes like trouts (McKay 1986;Perry 2005;Gjerde et al 1994, Quinton et al 2005, Bongers et al 1997) and guppy (Nakajima and Fujio 1993). The genetic correlation estimated for body weight and standard length was strong and positive (0.88±0.003).…”

Section: Breedingsupporting

confidence: 88%

Inbred zebrafish lines: A genetic repository for zebrafish researchers

Pathan¹,

Chaudhari²,

Krishna³

et al. 2019

IJGPB

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Genetically uniform strains/inbred strains of animals are used in experiments that demand minimal genetic background variability and highly reproducible results. Modern genomic research is heavily dependent on inbred strains and they are widely used for identification of quantitative loci that affect evolutionarily and biomedically important traits, dissection of gene-gene and gene environmental interaction patterns, toxicity studies, immunology, reverse genetics, cancer research, etc. In mice, over 450 inbred strains have been described and in medaka over 13 inbred strains have been established. Owing to its numerous attributes zebrafish, Danio rerio, is one of the widely studied vertebrate model organisms, but comparable zebrafish inbred strains are not available to the scientific community. This is because of early onset of inbreeding depression causing high mortality of embryos and larvae and biased sex ratio that have been reported from earlier attempts to produce inbred lines. At CZeBraG-Centre for Zebrafish Breeding and Genetics Research facility of ICARCIFE, the inbred lines of zebrafish are being developed. The strategy followed is intense inbreeding coupled with strong positive selection for selected traits. The base population consisted of three wild stocks of zebrafish collected from rivers of North East India. Using nested mating design 84 families were produced in F1 generation and 46 inbred families were produced in F2 generation. Genetic parameters for growth traits like body weight and standard length were estimated. The overall heritability for body weight and standard length was estimated using animal model and found to be 0.43 ± 0.05 and 0.36 ± 0.04 respectively. Fecundity was also recorded but showed no significant variation among stocks. Inbreeding depression was studied by comparing the population means for body weight and standard length of F1 and F2 generation. The analysis suggested there was no inbreeding depression. Genetic monitoring of zebrafish is conducted using microsatellite markers. New PCR primers were designed for 20 selected microsatellite loci with high stringency. High Resolution Melting Curve analysis was used for genotyping individual zebrafish. In addition to developing inbred lines the centre is also maintaining the wild zebrafish stocks and has commenced supply of pedigreed zebrafish for researchers. In future zebrafish of known inbred levels (12.5 to 50% and above) can be supplied. Currently, the CZeBraG can house about 10000 adults, with separate facility for holding individual fish.

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Section: Breedingsupporting

confidence: 88%

Inbred zebrafish lines: A genetic repository for zebrafish researchers

Pathan¹,

Chaudhari²,

Krishna³

et al. 2019

IJGPB

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“…This might have been the reason why the residual variance was overestimated. The estimated heritability for body weight in Japanese flounder was similar to that in Atlantic salmon and slightly lower than those for rainbow trout and carp [21][22][23][24][25][26]. The estimated heritabilities of body weight and body length were 0.09 and 0.16 at 150 days of age, 0.29 and 0.37 at 280 days of age, and 0.17 and 0.23 at 2.5 years of age, respectively, in rainbow trout [27,28].…”

Section: Discussionmentioning

confidence: 59%

Estimation of genetic parameters for growth traits of Japanese flounder Paralichthys olivaceus using an animal model

Liu

Wang

et al. 2010

Fish Sci

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To estimate genetic parameters of growth traits in Japanese flounder Paralichthys olivaceus, full-sib and half-sib families were produced in three consecutive years at the Beidaihe Central Experiment Station in China. Each year 8-28 families were produced. The body weight, body length and body depth at 180, 240, and 360 days of age were measured for 5,224 individuals. Four animal models were used to examine the phenotypic variation of growth traits and were compared using the likelihood ratio test. The results showed that estimates for additive genetic effect heritabilities varied greatly depending on the model, trait and age. The maternal effect had a significant impact on phenotypic variation only for body depth at 180 days of age, which explained 49% of the phenotypic variance. The ratio of full-sib effect to phenotypic variation ranged from 0.09 to 0.22. Growth traits all exhibited low heritability (0.13-0.39), indicating that there is the potential for family selection breeding for these traits in Japanese flounder. Using the full model with the fixed, full-sib family, additive and maternal genetic effects, genetic correlations among the three traits for fish of the same age were estimated to be more than 0.80. Generally, the genetic correlations gradually increased as age increased.

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“…The estimation methods of heritability in the common carp include parent-offspring regression (Nenashev, 1966;Zhang et al, 1981), family analysis (Nenashev, 1966; Nagy et al, 1980;Wang et al, 2006c), animal model (Bongers et al, 1997;Tanck et al, 2001), and mixed genetic model (Wang et al, 2006d). The existing environmental effects cause bias in parent-offspring regression.…”

Section: Heritabilitymentioning

confidence: 99%

Quantitative genetic estimates of growth-related traits in the common carp (Cyprinus carpio L.): A review

Wang

2009

Front. Biol. China

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The common carp (Cyrpinus carpio L.) is the oldest cultured and the most domesticated fish species, as well as one of the most important freshwater fishes in the world. However, scientific studies on evaluating the growth-related quantitative traits in this fish are limited. Heritability, the most important parameter in selective breeding programs, was extensively studied for the growth-related traits. The values varied widely among the experiments and methods used because of the existence of common environmental, dominance and maternal effects. However, correlations in phenotypic and genetic levels first evaluated several years ago were limited. On the other hand, heterosis was widely reported and easily obtained for growth-related traits in the common carp. Meanwhile, genotype environment interaction and prediction of breeding values have been studied recently, and are very important in conducting selective breeding programs. The developmental quantitative genetics of growth-related traits was first analyzed in the common carp for reasonable selection during ontogeny. It is expected that genetic improvement will be achieved by carrying out direct selective breeding in the common carp.

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Distribution of genetic variance in gynogenetic or androgenetic families

Cited by 23 publications

References 20 publications

Inbred zebrafish lines: A genetic repository for zebrafish researchers

Inbred zebrafish lines: A genetic repository for zebrafish researchers

Estimation of genetic parameters for growth traits of Japanese flounder Paralichthys olivaceus using an animal model

Quantitative genetic estimates of growth-related traits in the common carp (Cyprinus carpio L.): A review

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