Distribution of Ia-Positive Cells in the Pig and Human Pancreas

Parkkinen, Elke; Nordling, Stig; Puolakkainen, Pauli; Kiviluoto, Tuula; Schröder, T; Schröder, Jim

doi:10.1159/000128429

Cited by 1 publication

(1 citation statement)

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“…Ia antigens are expressed primarily on B lymphocytes. They were found also on the surface of activated T lymphocytes, dendritic cells, macrophages, Kupffer cells in the liver, Langerhans cells in the skin and on low levels on vascular endothelium and some tumor cells (HART/FABRE, 1981;SHACKELFORD et a]., 1982;BASHAM/MERIGAN, 1983;PARKKINEN et al, 1984;PESCOVITZ et al, 1984). Ia molecules participate in the antigen presentation to et al, 1977).…”

Section: Introductionmentioning

confidence: 99%

The Tissue Distribution of la‐ and IgM‐Positive Cells in Adult and Newborn Miniature Pigs

Horák

Hruban

Dvořák

1989

Anat Histol Embryol

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Distribution of Ia- and IgM-positive cells was compared in tissues of adult and newborn miniature pigs, using indirect immunoperoxidase and immunofluorescent techniques with monoclonal antibodies. The different distribution patterns were found mainly in adult jejunum and kidney. Both IgM- and Ia-staining were ascertained in the lamina propria between the Lieberkühn crypts and in the lymphoid follicles of the jejunum. Moreover, IgM-positive cells were demonstrated in the crypts while Ia-reaction was seen in the lamina propria of the villi. In the kidney, IgM-staining was limited to the glomeruli. On the contrary, a distinct Ia-reaction was found mainly in intertubular structures. Small differences in IgM- and Ia-positive cell distribution were also noted in the mesenteric lymph nodes and in the spleen. Developmental changes of the adult distribution patterns (chiefly that of IgM-positive cells) were found in all tissues studied at 2 days of age.

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Section: Introductionmentioning

confidence: 99%