Distribution of neurons in the lateral reticular nucleus projecting to cervical, thoracic, and lumbar segments of the spinal cord in the rat

Lee, Hyun Sook

doi:10.1080/12265071.2000.9647569

Cited by 2 publications

(3 citation statements)

References 29 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lateral reticular nucleus consists of parvocellular, magnocellular, and subtrigeminal divisions [69][70][71][72]. All output of the lateral reticular nucleus is directed to the cerebellum [73].…”

Section: Lateral Reticular Nucleus (Lrt)mentioning

confidence: 99%

A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals

2022

View full text Add to dashboard Cite

The cerebellum is involved in many motor, autonomic and cognitive functions, and new tasks that have a cerebellar contribution are discovered on a regular basis. Simultaneously, our insight into the functional compartmentalization of the cerebellum has markedly improved. Additionally, studies on cerebellar output pathways have seen a renaissance due to the development of viral tracing techniques. To create an overview of the current state of our understanding of cerebellar efferents, we undertook a systematic review of all studies on monosynaptic projections from the cerebellum to the brainstem and the diencephalon in mammals. This revealed that important projections from the cerebellum, to the motor nuclei, cerebral cortex, and basal ganglia, are predominantly di- or polysynaptic, rather than monosynaptic. Strikingly, most target areas receive cerebellar input from all three cerebellar nuclei, showing a convergence of cerebellar information at the output level. Overall, there appeared to be a large level of agreement between studies on different species as well as on the use of different types of neural tracers, making the emerging picture of the cerebellar output areas a solid one. Finally, we discuss how this cerebellar output network is affected by a range of diseases and syndromes, with also non-cerebellar diseases having impact on cerebellar output areas.

show abstract

Section: Lateral Reticular Nucleus (Lrt)mentioning

confidence: 99%

A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals

2022

View full text Add to dashboard Cite

show abstract

“…2E). Somatotopic organization of labeled neurons in the LRt has not been observed among injection cases at cervical, thoracic, or lumbar spinal cord (Lee, 2000).…”

Section: Resultsmentioning

confidence: 86%

“…2) or double-labeling (Figs. 3-8) studies indicated that the descending projection was not somatotopically organized (Lee, 2000). DBH-positive cells located at the perimeter of the LRt projected to the dorsal quadrant of cervical, thoracic, or lumbar spinal cord.…”

Section: Lumbar Injection Casesmentioning

confidence: 97%

Evidence that dopamine‐beta‐hydroxylase immunoreactive neurons in the lateral reticular nucleus project to the spinal cord in the rat

Lee¹,

Waterhouse²,

Mihailoff³

2001

Anat. Rec.

View full text Add to dashboard Cite

The existence of noradrenergic projections from the lateral reticular nucleus (LRt) to the dorsal quadrant of cervical, thoracic, or lumbar spinal cord was investigated using a combined method of WGA-apo-HRP-gold retrograde tracing and dopamine-beta-hydroxylase (DBH) immunocytochemistry. Preliminary retrograde tracing studies indicated that LRt neurons projecting to cervical, thoracic, or lumbar spinal cord were characteristically located near the perimeter of the LRt. Double-labeling experiments demonstrated that a portion of these peripherally-located, spinal-projecting neurons were DBH-immunoreactive. Double-labeled neurons were also located at the parvocellular division of the contralateral LRt in the thoracic injection cases. Double-labeled neurons were not observed at the subtrigeminal division in cervical, thoracic, or lumbar injection case. The results suggest the possibility that the noradrenergic LRt-spinal pathway might be involved in a variety of pain processing and cardiovascular regulatory functions in the rat.

show abstract

Distribution of neurons in the lateral reticular nucleus projecting to cervical, thoracic, and lumbar segments of the spinal cord in the rat

Cited by 2 publications

References 29 publications

A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals

A Systematic Review of Direct Outputs from the Cerebellum to the Brainstem and Diencephalon in Mammals

Evidence that dopamine‐beta‐hydroxylase immunoreactive neurons in the lateral reticular nucleus project to the spinal cord in the rat

Contact Info

Product

Resources

About