Distribution of SARS-CоV-2 seroprevalence among residents of the Tyumen Region during the COVID-19 epidemic period. Journal of microbiology, epidemiology and immunobiology

Abstract

Федеральная служба по надзору в сфере защиты прав потребителей и благополучия человека,

SARS-CoV-2 Seropositivity among Dental Staff and the Role of Aspirating Systems

“…In contrast to the findings reported from other countries, the prevalence of SARS-CoV-2 infection observed in this study was not associated with sex ( Consonni et al 2020 ; Razvi et al 2020 ) or position/role in the dental team ( Gómez-Ochoa et al 2021 ). The lack of a significant association with sex is consistent with previous population-based studies ( Barchuk et al 2020 ; Popova et al 2020 ) and could also be attributed to the insufficient power of statistical tests used. However, both dentists and dental assistants are in close contact with patients during treatment, which may explain the lack of differences in the risk of infection between these HCW categories.…”

Seroprevalence of SARS-CoV-2 Antibodies in Symptomatic Individuals Is Higher than in Persons Who Are at Increased Risk Exposure: The Results of the Single-Center, Prospective, Cross-Sectional Study

“…During the pandemic, the assessment of IgM and IgG has been used to diagnose COVID-19, allowing the evaluation of not only the cumulative prevalence of SARS-CoV-2 infection but also the monitoring of seroconversion at the individual and community levels [32,34]. The overall seropositivity estimate in the present study (28.33-28.53%) is similar to that reported from the general population of the Ural Federal District of Russia (24.5-31.3%), which comprises six federal districts: the Tyumen Region, Chelyabinsk Oblast, and Republic of Tatarstan [25,26]. However, our observed seroprevalence is significantly higher than the earlier estimate of 9-10.8% from May to June [24]; this reflects the gradual development of herd immunity and that SARS-CoV-2 continues to spread through the population, resulting in more symptomatic infections and, thus, more seropositive individuals.…”

“…Based on this, we initially assumed that the seroprevalence levels in the high-risk group would be near the upper limit of the general population. However, SARS-CoV-2 antibodies were only detected in 28.38% (adjusted prevalence 28.33-28.53%) of cases, which is significantly lower than the seroprevalence of the general population in neighboring regions [26,27]. The lower seroprevalence may be attributed to greater availability and enforcement of healthcare protocols, as well as the use of adequate personal protective equipment.…”

“…Although the COVID-19 outbreak in Russia started later compared to many neighboring European countries, Russia is currently among the six countries with the highest number of confirmed COVID-19 cases, as of 9 May 2021 [22,23]. Limited data suggest that the seroprevalence of SARS-CoV-2 infection in Russia was approximately 9-10% in May-June 2020 [24], reaching 19.6-31.3% [25][26][27] by the end of the year. At present, there are no data for seropositivity rates in specific cohorts, such as those with a high risk of occupational exposure to SARS-CoV-2.…”

Features of change of immune status indicators in individuals with active and latent forms of herpes-virus infections

“…Выявленное в нашем исследовании дос товерное увеличение средних уровней IgА, IgM, IgG и ЦИК весной 2020 г. указывает на более высокую распространенность острой инфекционной патологии в группе обследо ванных в этот период времени. Можно пред положить, что такие изменения показателей сопряжены с сезонным ростом заболеваемо сти ОРВИ и гриппом или распространением новой коронавирусной инфекции COVID 19 [45,46].…”