Distribution of Suicin Gene Clusters in<i> Streptococcus suis</i> Serotype 2 Belonging to Sequence Types 25 and 28

Athey, Taryn; Vaillancourt, Katy; Frenette, Michel; Fittipaldi, Nahuel; Gottschalk, Marcelo; Grenier, Daniel

doi:10.1155/2016/6815894

Cited by 7 publications

(3 citation statements)

References 15 publications

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“…Three suicin synthesis clusters have been described in S. suis: suicin 65, 90-1330, and 3908 synthesis clusters [28][29][30]. These clusters have already been described in the ST25 and ST28 strains analyzed in this study [31].…”

Section: Suicin Synthesis Clusters Carried By Ices In S Suissupporting

confidence: 71%

Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes

et al. 2019

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Streptococcus suis is a zoonotic pathogen suspected to be a reservoir of antimicrobial resistance (AMR) genes. The genomes of 214 strains of 27 serotypes were screened for AMR genes and chromosomal Mobile Genetic Elements (MGEs), in particular Integrative Conjugative Elements (ICEs) and Integrative Mobilizable Elements (IMEs). The functionality of two ICEs that host IMEs carrying AMR genes was investigated by excision tests and conjugation experiments. In silico search revealed 416 ICE-related and 457 IME-related elements. These MGEs exhibit an impressive diversity and plasticity with tandem accretions, integration of ICEs or IMEs inside ICEs and recombination between the elements. All of the detected 393 AMR genes are carried by MGEs. As previously described, ICEs are major vehicles of AMR genes in S. suis. Tn5252-related ICEs also appear to carry bacteriocin clusters. Furthermore, whereas the association of IME-AMR genes has never been described in S. suis, we found that most AMR genes are actually carried by IMEs. The autonomous transfer of an ICE to another bacterial species (Streptococcus thermophilus)—leading to the cis-mobilization of an IME carrying tet(O)—was obtained. These results show that besides ICEs, IMEs likely play a major role in the dissemination of AMR genes in S. suis.

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Section: Suicin Synthesis Clusters Carried By Ices In S Suissupporting

confidence: 71%

Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes

et al. 2019

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“…Interestingly, all three producing strains were non-virulent in mouse/pig infection models, and two of them were isolated from healthy carrier pigs [ 93 – 95 ]. The distribution of suicin gene clusters in S. suis serotype 2 belonging to sequence type (ST) 25 and ST28, the two dominant STs in North America, was recently investigated [ 96 ]. The gene clusters encoding suicin 65 (mostly in ST25 strains) and, to a lesser extent, suicin 90–1330 (exclusively in ST28 strains) are the most prevalent.…”

Section: Bacteriocins In Poultry and Swine Productionmentioning

confidence: 99%

Antimicrobial potential of bacteriocins in poultry and swine production

Lagha

Haas

Gottschalk

et al. 2017

Vet Res

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126

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The routine use of antibiotics in agriculture has contributed to an increase in drug-resistant bacterial pathogens in animals that can potentially be transmitted to humans. In 2000, the World Health Organization identified resistance to antibiotics as one of the most significant global threats to public health and recommended that the use of antibiotics as additives in animal feed be phased out or terminated, particularly those used to treat human infections. Research is currently being carried out to identify alternative antimicrobial compounds for use in animal production. A number of studies, mostly in vitro, have provided evidence indicating that bacteriocins, which are antimicrobial peptides of bacterial origin, may be promising alternatives to conventional antibiotics in poultry and swine production. This review provides an update on bacteriocins and their potential for use in the poultry and swine industries.

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“…parasuis, a potential opportunistic zoonotic pathogen is also close relative of Streptococcus suis (S. suis), initially classified as S. suis serotypes 20, 22 and 26 [29,30] . S. suis is reported to produce suicin 3908 and suicin 90-1330 [31,32] . S. agalactiae is a Group B Beta-hemolytic Streptococcus (GBS).…”

Section: Isolate Namementioning

confidence: 99%

Isolation and Identification of Bacteriocin Producing Microbial Strains from Rhizosphere Soil

Vahid,

Mallik,

Tyagi

2024

IJPS

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Isolation and Identification of Bacteriocin Producing Microbial StrainsEmergence and spread of antibiotics resistance among bacteria poses a serious concern for human health and disease therapy. In addition to this, novel pathogens are also surfacing rapidly. Discovery and development of newer, potent antimicrobial and therapeutic agents is constantly required. Soil is perplexing at different climatic conditions thereby providing variable source for the production of antibiotic producing microorganisms. Bacteriocin is a proteinaceous substance produced by bacteria which inhibits the growth of closely or exactly related bacterial strains. It is natural, safe secondary metabolite and its development and need for better antibiotic spectrum is always in high demand. In the present investigation, the bacteriocin producing microorganisms were isolated from the local rhizospheric soil samples. The isolates were subject to antibacterial susceptibility test against the common pathogenic bacteria i.e., Pseudomonas, Aeromonas, Bacillus and Escherichia coli by agar well diffusion method. The prominent zone of inhibition shown by isolate strains was recorded. Out of the 11 isolates, 5 isolated bacterial strains displayed significant inhibitory activity against the pathogenic bacteria. For further identification, biochemical tests were performed for these strains. These bacterial strains were identified with high similarity to Streptococcus sp., Enterococcus and Gemella berger. This investigation indicates that these bacteria have great potential for the production of antimicrobial property and this can be further characterized and utilized to control the growth of microbes in the future.

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Distribution of Suicin Gene Clusters in Streptococcus suis Serotype 2 Belonging to Sequence Types 25 and 28

Cited by 7 publications

References 15 publications

Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes

Chromosomal Conjugative and Mobilizable Elements in Streptococcus suis: Major Actors in the Spreading of Antimicrobial Resistance and Bacteriocin Synthesis Genes

Antimicrobial potential of bacteriocins in poultry and swine production

Isolation and Identification of Bacteriocin Producing Microbial Strains from Rhizosphere Soil

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