Disturbance of verticality perception and postural dysfunction in Parkinson's disease

Schindlbeck, Katharina A.; Naumann, Wanda; Maier, André; Ehlen, Felicitas; Marzinzik, Frank; Klostermann, Fabian

doi:10.1111/ane.12859

Cited by 22 publications

(12 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For example, Cano Porras et al recently reported that mere downward visual perturbations (platform "drops" down) generated in a VR system can trigger characteristic muscle activation patterns in standing individuals (Cano Porras et al, 2021). In summary, while visual cues have a transiently significant contribution that wears off (Schindlbeck et al, 2018), body-based cues continuously adjust during walking in response to walking speed.…”

Section: Discussionmentioning

confidence: 99%

Vision Affects Gait Speed but not Patterns of Muscle Activation During Inclined Walking—A Virtual Reality Study

Benady

Zadik

Ben-Gal

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

While walking, our locomotion is affected by and adapts to the environment based on vision- and body-based (vestibular and proprioception) cues. When transitioning to downhill walking, we modulate gait by braking to avoid uncontrolled acceleration, and when transitioning to uphill walking, we exert effort to avoid deceleration. In this study, we aimed to measure the influence of visual inputs on this behavior and on muscle activation. Specifically, we aimed to explore whether the gait speed modulations triggered by mere visual cues after transitioning to virtually inclined surface walking are accompanied by changes in muscle activation patterns typical to those triggered by veridical (gravitational) surface inclination transitions. We used an immersive virtual reality system equipped with a self-paced treadmill and projected visual scenes that allowed us to modulate physical–visual inclination congruence parametrically. Gait speed and leg muscle electromyography were measured in 12 healthy young adults. In addition, the magnitude of subjective visual verticality misperception (SVV) was measured by the rod and frame test. During virtual (non-veridical) inclination transitions, vision modulated gait speed by (i) slowing down to counteract the excepted gravitational “boost” in virtual downhill inclinations and (ii) speeding up to counteract the expected gravity resistance in virtual uphill inclinations. These gait speed modulations were reflected in muscle activation intensity changes and associated with SVV misperception. However, temporal patterns of muscle activation were not affected by virtual (visual) inclination transitions. Our results delineate the contribution of vision to locomotion and may lead to enhanced rehabilitation strategies for neurological disorders affecting movement.

show abstract

Section: Discussionmentioning

confidence: 99%

Vision Affects Gait Speed but not Patterns of Muscle Activation During Inclined Walking—A Virtual Reality Study

Benady

Zadik

Ben-Gal

et al. 2021

Front. Bioeng. Biotechnol.

View full text Add to dashboard Cite

show abstract

“…The brain areas related to verticality perception described by neuroimaging studies involve the parietal cortex, superior and middle temporal gyrus, temporo-parietal junction, post central gyrus, inferior frontal gyrus, insula, and thalamus [ 4 – 11 ]. Altered verticality perception has been described in aged people [ 12 ], patients with vestibular disorders [ 13 ], Parkinson’s disease [ 14 ], idiopathic scoliosis [ 15 ], and stroke patients [ 5 ]. Recently, verticality perception was further associated with postural control and functionality in stroke patients [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Normative data for human postural vertical: A systematic review and meta-analysis

et al. 2018

View full text Add to dashboard Cite

Perception of verticality is required for normal daily function, yet the typical human detection error range has not been well characterized. Vertical misperception has been correlated with poor postural control and functionality in patients after stroke and after vestibular disorders. Until now, all the published studies that assessed Subjective Postural Vertical (SPV) in the seated position used small groups to establish a reference value. However, this sample size does not represent the healthy population for comparison with conditions resulting in pathological vertical. Therefore, the primary objective was to conduct a systematic review with meta-analyses of Subjective Postural Vertical (SPV) data in seated position in healthy adults to establish the reference value with a representative sample. The secondary objective was to investigate the methodological characteristics of different assessment protocols of SPV described in the literature. A systematic literature search was conducted using Medline, EMBASE, and Cochrane libraries. Mean and standard deviation of SPV in frontal and sagittal planes were considered as effect size measures. Sixteen of 129 identified studies met eligibility criteria for our systematic review (n = 337 subjects in the frontal plane; n = 187 subjects in sagittal plane). The meta-analyses measure was estimated using the pooled mean as the estimator and its respective error. Mean reference values were 0.12°±1.49° for the frontal plane and 0.02°±1.82° for the sagittal plane. There was a small variability of the results and this systematic review resulted in representative values for SPV. The critical analysis of the studies and observed homogeneity in the sample suggests that the methodological differences used in the studies did not influence SPV assessment of directional bias in healthy subjects. These data can serve as a reference for clinical studies in disorders of verticality.

show abstract

“…There are two tools that are commonly used to measure the visual perception of verticality: The subjective visual vertical test (SVV) and the rod and frame test (RFT). Different studies looking into perception of visual verticality have revealed that it is impaired in neurological disorders such as stroke [ 73 , 74 , 75 ], Parkinson’s disease [ 76 , 77 ], multiple sclerosis [ 78 ], vestibular dysfunctions [ 79 , 80 , 81 ], chronic dizziness [ 82 ], and type II diabetes mellitus [ 83 ], among others.…”

Section: Discussionmentioning

confidence: 99%

Visual Verticality Perception in Spinal Diseases: A Systematic Review and Meta-Analysis

Obrero‐Gaitán

Molina

Casado

et al. 2020

JCM

View full text Add to dashboard Cite

Patients diagnosed with traumatic or non-traumatic spinal pain and idiopathic scoliosis frequently suffer from imbalance. The evaluation of the perception of verticality by means of visual tests emerges as a quick and easy tool for clinical management of the balance disorders. Several studies have assessed the visual perception of verticality in spinal diseases obtaining controversial results. The aim of our study is to analyze the perception of visual verticality in subjects with several spinal diseases in comparison with healthy subjects. A meta-analysis was carried out. PubMed MEDLINE, Scopus, WoS, CINAHL, and SciELO databases were searched until January 2020. The standardized mean difference (SMD) was calculated to analyze differences between patients and healthy controls. Fifteen studies with a total of 2052 patients were included. In comparison with healthy subjects, a misperception of verticality was found in patients with spinal pain when the perception of the verticality was assessed with the rod and frame test (SMD = 0.339; 95% confidence interval (CI) = 0.181, 0.497; p < 0.001). It seems that the perception of visual verticality is not altered in patients with idiopathic scoliosis (p = 0.294). The present meta-analysis shows a misperception of visual verticality only in patients with spinal pain.

show abstract

Disturbance of verticality perception and postural dysfunction in Parkinson's disease

Abstract: Visual verticality perception in PD is deviated already in early stages, conceivably as a relatively static internal misrepresentation of object orientation. Variability about verticality perception emerges in more advanced stages and is associated with postural and balance abnormalities.

Cited by 22 publications

References 33 publications

Vision Affects Gait Speed but not Patterns of Muscle Activation During Inclined Walking—A Virtual Reality Study

Vision Affects Gait Speed but not Patterns of Muscle Activation During Inclined Walking—A Virtual Reality Study

Normative data for human postural vertical: A systematic review and meta-analysis

Visual Verticality Perception in Spinal Diseases: A Systematic Review and Meta-Analysis

Contact Info

Product

Resources

About