Diterpenoids

Hanson, J. R.

doi:10.1039/np9870400399

Cited by 17 publications

(6 citation statements)

References 35 publications

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“…Repellent for predatory starfish [36,39] Trimusculus costatus Toxic to Artemia salina and inhibitor feeding of the predatory fish Pomadasys commersonnii [38] Trimusculus peruvianus Antimicrobial activity [37,38,40,107] Mycale Cytotoxicity; antiviral, antimicrobial activities [45,68] Further more although the majority of the diterpenoids possess a trans relationship between H-9 and the C-10 methyl group, there are some examples of compounds that must be derived via a bicyclic precursor with a cis relationship between H-9 and the C-10 methyl group [18,19]. Subsequent modifications of the labdanediol may lead to compounds related to manool 11 and to labdanolic acid 12 [20] and agathic acid 13 and its derivatives.…”

Section: Trimusculus Conica Trimusculus Reticulatusmentioning

confidence: 99%

Labdanes of Natural Origin-Biological Activities (1981-2004)

Chinou

2005

CMC

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Terpenoids is a class of natural compounds found in higher plants, mosses, liverworts, algae and lichens, as well as in insects, microbes or marine organisms. Through centuries many of these compounds have been used as ingredients of perfumes, drugs, narcotics or pigments. Labdanes, belonging to the bicyclic diterpenoids group, have been found as secondary metabolites in tissues of fungi, insects, marine organisms, and in essential oils, resins and tissues of higher plants. The diterpenes of labdane type, have been reported to have broad spectrum of biological activities. In this study, the reported bioactivities and/or uses of them, the last two decades (1981-2004), are selected as an attempt to underline their role in nature.

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Section: Trimusculus Conica Trimusculus Reticulatusmentioning

confidence: 99%

Labdanes of Natural Origin-Biological Activities (1981-2004)

Chinou

2005

CMC

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“…Cyrneines are cyathanes isolated from the mushroom Sarcodon cyrneus. Nigernins, Onychiols, and Other Derivatives [104][105][106][107][108][109][110][111] Nigernins A-F 171-176 are cyathanes isolated from the fruiting bodies of basideomycete Phellodon niger. 5.9; Table 5.8).…”

Section: Cyathane Familymentioning

confidence: 99%

7-6-5 Tricarbocyclic Diterpenes

Marcos

Moro

Gil-Mesón

et al. 2016

Studies in Natural Products Chemistry

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“…Populusone belongs to the cembrane diterpenoid family, natural products that are commonly present in marine organisms such as corals . However, thus far, only a few cembrane diterpenoids have been isolated from terrestrial plants despite the fact that they were first discovered in tobacco and Pinus plants. − …”

mentioning

confidence: 99%

Discovery of Populusone, a Skeletal Stimulator of Umbilical Cord Mesenchymal Stem Cells from Populus euphratica Exudates

et al. 2019

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Populusone (1), a cembrane-type macrocyclic trinorditerpenoid, was isolated from the exudates of Populus euphratica and shown to have an unprecedented carbon skeleton, The structure was identified using spectroscopic methods and X-ray crystallography. A possible pathway for the biosynthesis of 1 was proposed. Populusone (10 μM) was found to promote proliferation and differentiation of umbilical cord derived mesenchymal stem cells into keratinocyte like cells.

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Diterpenoids

Cited by 17 publications

References 35 publications

Labdanes of Natural Origin-Biological Activities (1981-2004)

Labdanes of Natural Origin-Biological Activities (1981-2004)

7-6-5 Tricarbocyclic Diterpenes

Discovery of Populusone, a Skeletal Stimulator of Umbilical Cord Mesenchymal Stem Cells from Populus euphratica Exudates

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