Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers

Lemus, Igor; Garcı́a, Ricardo; Erazo, Silvia; Peña, Rafael Arriaza; Parada, Mirtha; Fuenzalida, M.

doi:10.1016/0378-8741(96)01444-4

Cited by 27 publications

(14 citation statements)

References 4 publications

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“…It occupies a range from southern Argentina and Chile north through Peru, Bolivia, Ecuador, Colombia, western Venezuela in South America continuing to Panama and Costa Rica in Central America . Although the species is used as a diuretic in traditional folk medicine of the indigenous people of this continent, it plays no commercial or pharmaceutical role in Europe or anywhere else in the world.…”

Section: Resultsmentioning

confidence: 99%

HILIC HPLC‐ESI‐MS/MS identification and quantification of the alkaloids from the genus Equisetum

Tipke

Bücker

Middelstaedt

et al. 2019

Phytochemical Analysis

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Introduction The plant family Equisetaceae (Equisetopsida, Monilophyta; common name: horsetails) is part of an ancient group of spore producing plants. Today, Equisetum is the only surviving genus comprising 15 species in two subgenera (Equisetum and Hippochaete). Several unique alkaloids are described to occur in this genus, so far there is very little data on the occurrence and the amount of those alkaloids for the different species. Objective To establish an extraction method and an analytical method to detect and quantify the relevant Equisetum‐type alkaloids and to create a quantitative data set on the alkaloid content of all Equisetum species worldwide. Methodology Hydrophilic interaction liquid chromatography high‐performance liquid chromatography tandem mass spectrometry (HILIC HPLC‐MS/MS) in electrospray ionisation (ESI) positive mode was used to analyse and quantify the alkaloid content of 68 Equisetum samples. Results The presence of nicotine in at least one sample of each Equisetum species could be demonstrated. The total nicotine amount rarely exceeded 250 μg/kg and 50 μg/kg for the subgenus Equisetum and Hippochaete, respectively. Besides nicotine, Equisetum‐type alkaloids (mainly palustrine and palustridiene) were only detected in three species, namely E. palustre, E. bogotense and E. giganteum. For E. giganteum, palustridiene was detected at levels around the limit od detection (LoD) (25 μg/kg), whereas in E. palustre and E. bogotense, both alkaloids (palustrine and palustridiene) were detected at much higher levels (20–800 mg/kg). Conclusions All Equisetum species occurring worldwide were successfully subjected to a detailed qualitative and quantitative alkaloid analysis using a newly developed HILIC‐HPLC‐ESIpos‐MS/MS approach. The data set can be used to distinguish different Equisetum‐chemotypes.

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Section: Resultsmentioning

confidence: 99%

HILIC HPLC‐ESI‐MS/MS identification and quantification of the alkaloids from the genus Equisetum

Tipke

Bücker

Middelstaedt

et al. 2019

Phytochemical Analysis

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“…Andean Horsetail Y Stem Lemus et al (1996) Ali et al, 2003); fruit (Al Ali et al, 2003;Singh and Sisodia, 1971) Al Ali et al (2003), Singh and Sisodia (1971) Note that common names were identified by referring to research articles and visiting http://plants.usda.gov. Study refers to the design (P, parallel; CO, cross-over), whether the study was randomised (R?…”

Section: Equisetum Bogotense Kunthmentioning

confidence: 97%

“…In Chile and Mexico, Equisetum has traditional uses as a diuretic and a means of treating kidney stones. It has also been used for polishing copper utensils, cleansing teeth (Perez Gutierrez et al, 1985;Lemus et al, 1996) and to have anti-diabetic (Andrade-Cetto and Heinrich, 2005) and platelet sedating effects (Mekhfi et al, 2004).…”

Section: Equisetaceaementioning

confidence: 99%

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Herbal medicines as diuretics: A review of the scientific evidence

Wright

Van-Buren

Kroner

et al. 2007

Journal of Ethnopharmacology

240

122

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“…Indeed, promising effects were seen in the human trial by Lemus et al [2] and a study in conscious animals by Perez Gutierrez et al [3]. Of course more studies in humans are required in order to assess and compare the most effective candidates.…”

Section: Resultsmentioning

confidence: 85%

Herbal Diuretics

IW¹

2016

J Nutr Food Sci

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EditorI would like to challenge your readership to read 'Herbal medicines as diuretics: A review of the scientific evidence' [1] which is extremely well read and cited since being published, suggesting that in the age when healthcare costs are increasing, there may be a place for herbals as a first-line or adjunct therapy in the management of hypertension. But, at the present time, more research and data is still needed to demonstrate the effect of herbals in controlled interventional trials.The World Health Federation (see www.world-heart-federation.org) state that worldwide there are around 970 million people with hypertension (i.e., elevated blood pressure) and the World Health Organization considers this to be one of the most important causes of premature death. Indeed, by 2025, it is estimated that 1.6 billion adults will be living with hypertension.There are a number of therapies that can be used clinically to manage hypertension. These include the use of angiotensin converting enzyme inhibitors, beta blockers, calcium channel blockers and diuretics. This latter class work by increasing the excretion from the body of urine and sodium in urine. The review 'Herbal medicines as diuretics: A review of the scientific evidence' [1] assesses the studies reporting diuretic effects with traditional / herbal medicines as it was unclear which plant extracts actually had an effect similar to those used in clinical practice. A literature search was conducted to: (1) capture the pool of studies performed in this area; (2) identify which extracts had been reported in the studies identified; (3) determine the effect of these extracts on urinary volume and urinary sodium excretion. From this it was possible to assess the support for specific extracts and to recommend potential candidates for future research and potential use.A search of Medline was conducted and studies identified were graded according to the results reported. The Medline search included all English language articles published containing the following terms: natriuresis, natriuretic, diuresis, diuretic, aquaretic and urinary flow. These were combined with the following search terms: food, herb, botanical, nutrient and extract. The plants identified were then confirmed using http://www.ipni.org. None traditional extracts, e.g., caffeine and polyherbal preparation Jawarish Zarooni Sada, were excluded, as were vitamins and minerals.Seventy-seven articles were identified and reviewed; however, of more note is the fact that only nine of these were conducted in human intervention trials. Table 1 summarizes these studies by extract and also includes the study design and the responses in terms of urinary volume and urinary sodium excretion. Other studies were also highlighted, as they are supporting evidence, with 13 studies identified in anaesthetised animals and 55 studies in conscious animals.

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Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers

Cited by 27 publications

References 4 publications

HILIC HPLC‐ESI‐MS/MS identification and quantification of the alkaloids from the genus Equisetum

HILIC HPLC‐ESI‐MS/MS identification and quantification of the alkaloids from the genus Equisetum

Herbal medicines as diuretics: A review of the scientific evidence

Herbal Diuretics

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