Diurnal changes in blood ketone bodies, glucose and lipids according to energy intake in adult sheep

Abstract

Summary. In order to establish the daily evolution of different blood components according to energy intake in sheep, blood samples were taken every hour during three periods of 24 or 48 hrs. The animals were underfed, fed at maintenance level or fed ad libitum. A rapid increase of blood acetoacetate and !-hydroxybutyrate generally occurred 1 to 2 hrs after feeding. Daily fluctuations were larger in animals fed in a limited way than in those fed ad libitum. The mean daily blood concentration of ketone bodies depended more on individual differences than on the intake level. Food ingestion also induced an increase of glycemia, but it was not as evident as that of the ketone bodies and occurred later (3 or 4 hrs after feeding) ; glycemia also appeared to increase during the night. The level of food intake had no effect on mean blood glucose content nor on its evolution during the day. We could not conclude that there was an evolution of blood lipids in regard to their distribution, FFA content or FFA distribution during the day. It was also impossible to demonstrate an effect of food level intake on the blood lipids.Introduction.

Influence of the state of fatness on body composition and blood constituents (lipids, glucose, ketone bodies and insulin) in adult sheep

“…Concentrates and hay used were the same as in previous long-term feeding experiment (VANDERMEERSCHEN-DOIZE et al 1982). The procedures used to measure blood glucose, ketone bodies, insulin and non esterified fatty acids (FFA) concentrations, to estimate blood lipid and fatty acid compositions and to determine the body composition were described previously (DOIZE et al 1979;VANDERMEERSCHEN-DOIZE et al 1982, 1983.…”