Diurnal Fluoride Concentration in Whole Saliva in Children Living in a High- and a Low-Fluoride Area

Oliveby, A.; Twetman, Svante; Ekstrand, Jan

doi:10.1159/000261237

Cited by 44 publications

(25 citation statements)

References 12 publications

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“…There is no measurable additional effect of having teeth formed under the exposure to fluoridated water, but only of having teeth continuously bathed by fluoride-enriched saliva. Since the concentration of fluoride needed to control caries is within a micromolar range, a small increase in fluoride concentration in saliva of people living in a fluoridated area (about 0.02 ppm F), when compared to those living in a non-fluoridated area (about 0.01 ppm F), 16 has a tremendous effect.…”

Section: Community-based Methods Of Fluoride Usementioning

confidence: 99%

Fluoride: its role in dentistry

Tenuta¹,

2010

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In spite of decades of research on fluoride and the recognition of its role as the cornerstone of dental caries reduction in the last fifty years, questions still arise on its use at community, self-applied and professional application levels. Which method of fluoride delivery should be used? How and when should it be used? How can its benefits be maximized and still reduce the risks associated with its use? These are only some of the challenging questions facing us daily. The aim of this paper is to present scientific background to understand the importance of each method of fluoride use considering the current caries epidemiological scenario, and to discuss how individual or combined methods can be used based on the best evidence available.

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Section: Community-based Methods Of Fluoride Usementioning

confidence: 99%

Fluoride: its role in dentistry

Tenuta¹,

2010

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“…Fifty microlitres of 7.5 mol/l acetate buffer (pH 5.0) containing 2% CDTA was added to 450 µl of the standard solution or the sample. The precision of the method has been shown to be 8.3 and 13.3% (coefficient of variation) at 0.89 and 0.40 µmol/l, respectively [Oliveby et al, 1990].…”

Section: Fluoride Determinationmentioning

confidence: 95%

Fluoride Concentration in Whole Saliva and Separate Gland Secretions in Schoolchildren after Intake of Fluoridated Milk

Twetman¹,

Nederfors²

1998

Caries Res

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Fluoride concentration in whole saliva and in separate gland secretions was studied after a 7–day fluoridated milk regimen (1mg F per day) in 12 healthy schoolchildren aged 10–13 years. A 2–week fluoride–free run–in period preceded the tests in order to establish the endogenous baseline levels. Unstimulated and stimulated whole saliva and stimulated parotid and submandibular–sublingual saliva were collected at 1, 3, 6, 12 and 24h after F–milk ingestion, and fluoride concentrations were determined with an ion–selective electrode. Typical time–dependent excretion curves were obtained in all collected secretions. The fluoride levels were significantly elevated 1 and 3h in whole saliva and up to 6h in the gland secretions after intake of fluoridated milk when compared to baseline values. When acid–stimulated, the submandibular–sublingual glands were the major contributors of fluoride in the oral cavity. In conclusion, the results of this study demonstrate that fluoride ingested with milk is excreted through the salivary glands, indicating that the bioavailability of fluoride from milk equals that of other vehicles.

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“…Several standard points were used below 0.02 mg F/l in order to construct the non-linear part of the standard curve. The precision of this method has been determined in a previous report [Oliveby et al, 1990].…”

Section: Fluoride Determinationmentioning

confidence: 99%

Fluoride Concentrations in Saliva and Dental Plaque in Young Children after Intake of Fluoridated Milk

Petersson

Arvidsson²,

Lynch³

et al. 2002

Caries Res

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This study determined fluoride (F) concentrations in whole saliva and dental plaque after intake of fluoridated milk using a randomised crossover experimental design. Eighteen healthy children (6–8 years) were subjected to each of four different 3-day drinking regimens: (a) 200 ml F-free tap water; (b) 200 ml tap water with 1.0 mg F; (c) 200 ml standard milk, and (d) 200 ml standard milk with 1.0 mg F. A washout period of 7 days was organised between the different drinking regimens. All children used F-free toothpaste prior to and during the trial and were instructed to avoid F-rich food and drinks. F concentration in unstimulated whole saliva was determined at baseline and after 15 and 120 min and in plaque samples at baseline and after 2 h. The mean baseline values ranged from 0.01 to 0.02 mg F/l in saliva and between 10.4 and 14.2 mg F/l in dental plaque. A statistically significant (p < 0.05) increase of F was disclosed in saliva 15 min after drinking F-containing milk and water (0.052 and 0.058 mg F/l, respectively). After 2 h, the salivary F^– concentrations were back to baseline values. In the plaque, however, a statistically significant (p < 0.01) twofold increase was found at 2 h after the intake of fluoridated milk and water, respectively. The results indicate that consumption of fluoridated milk contributes to a F storing process with significantly elevated F concentrations in dental plaque up to 2 h after intake. Further studies are required to determine the ‘therapeutic concentration’ of F in dental plaque after intake of fluoridated milk.

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Diurnal Fluoride Concentration in Whole Saliva in Children Living in a High- and a Low-Fluoride Area

Cited by 44 publications

References 12 publications

Fluoride: its role in dentistry

Fluoride: its role in dentistry

Fluoride Concentration in Whole Saliva and Separate Gland Secretions in Schoolchildren after Intake of Fluoridated Milk

Fluoride Concentrations in Saliva and Dental Plaque in Young Children after Intake of Fluoridated Milk

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