Diurnal profiles of plasma magnesium and blood glucose in diabetes

Mather, H.; Levin, G. E.; Nisbet, J A; Hadley, Lindsay; Oakley, N. W.; Pilkington, T. R. E.

doi:10.1007/bf00283749

Cited by 26 publications

(12 citation statements)

References 9 publications

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“…(4). A few case of diabetes were given magnesium sulfate intravenously for several months showed decrease of blood glucose and HbA1~ (unpublished observations).…”

Section: Methods and Subjectsmentioning

confidence: 94%

Hypertension and Serum Mg in the Patients with Diabetes and Coronary Heart Disease

Nagase

1996

Hypertens Res

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Interrelations between hypertension (HT), ischemic heart disease (IHD) and diabetes mellitus (DM) were investigated in the diabetic subjects without IHD (DM group) or with IHD (DM + IHD group) and subjects with IHD (IHD group) which were not complicated with DM. 1. The incidence of hypertension of DM group, DM + IHD group and IHD group is 40, 54, 38% respectively. 2. The incidence of hyperlipidemia of DM group, DM + IHD group and IHD group is 55, 71, 56% respectively. 3. Serum Mg levels of DM (1.9 ± 0.37 mg/dl), DM + IHD (1.8 ± 0.23) and IHD (1.9 ± 0.33) were significantly lower than that of normal control (2.3 ± 0.32). 4. Serum Mg level of poorly controlled diabetic patients is lower than that of well controlled diabetic patients. These results suggested that Magnesium deficient state is one of the cause of insulin resistancy. (Hypertens Res 1996; 19 Suppl. I: 565-568)

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“…(4). A few case of diabetes were given magnesium sulfate intravenously for several months showed decrease of blood glucose and HbA1~ (unpublished observations).…”

Section: Methods and Subjectsmentioning

confidence: 94%

Hypertension and Serum Mg in the Patients with Diabetes and Coronary Heart Disease

Nagase

1996

Hypertens Res

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“…Peroxidation of lipoproteins due to free radical production and increased platelet aggregation may also contribute to the development of atherosclerosis. Seelig and Hegetveit [89] and Mathur [90] have suggested that magnesium can prevent atherosclerotic disease by counteracting the adverse effect of excessive intracellular calcium, retaining intracellular potassium and contributing both to stabilize the plasma membrane and maintaining the integrity of subcellular structures. VanRoelen et al [91] also confirmed the negative correlation between poor erythrocyte magnesium content and severity of the microangiopathy.…”

Section: Magnesium and Cardiovascular Diseasesmentioning

confidence: 99%

Implications of Magnesium Deficiency in Type 2 Diabetes: A Review

Chaudhary

Sharma

Bansal

2009

Biol Trace Elem Res

139

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Magnesium is the fourth most abundant cation in the body and plays an important physiological role in many of its functions. It plays a fundamental role as a cofactor in various enzymatic reactions involving energy metabolism. Magnesium is a cofactor of various enzymes in carbohydrate oxidation and plays an important role in glucose transporting mechanism of the cell membrane. It is also involved in insulin secretion, binding, and activity. Magnesium deficiency and hypomagnesemia can result from a wide variety of causes, including deficient magnesium intake, gastrointestinal, and renal losses. Chronic magnesium deficiency has been associated with the development of insulin resistance. The present review discusses the implications of magnesium deficiency in type 2 diabetes.

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“…Experimental magnesium de fi ciency is characterized by increased triglycerides, cholesterol, VLDL, LDL, apolipoprotein B and triglyceride-rich lipoproteins A1, and plasma lecithin-cholesterol acyltransferase activity [ 69 ] . Magnesium can prevent atherosclerotic disease by counteracting the adverse effect of excessive intracellular calcium, retaining intracellular potassium, and contributing both to stabilize the plasma membrane and to maintain the integrity of subcellular structures [ 70,71 ] . Magnesium supplementation of hyperlipidemic subjects has been shown to cause a reduction in total and LDL cholesterol and apolipoprotein B and an increase in HDL cholesterol and triglycerides [ 67 ] .…”

Section: Magnesium De Fi Ciency and Type 2 Diabetesmentioning

confidence: 99%

Magnesium Deficiency in Type 2 Diabetes

Chaudhary

2012

Magnesium in Human Health and Disease

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Key PointsMagnesium is the second most abundant intracellular cation which is widely distributed in plant • and animal foods. Magnesium de fi ciency is actually fairly common, and low magnesium intake may play a role in the • development of type 2 diabetes. Magnesium supplementation has been shown to improve insulin sensitivity and diabetes mellitus. • Magnesium de fi ciency is associated with the development of atherosclerotic cardiovascular • diseases.

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Diurnal profiles of plasma magnesium and blood glucose in diabetes

Cited by 26 publications

References 9 publications

Hypertension and Serum Mg in the Patients with Diabetes and Coronary Heart Disease

Hypertension and Serum Mg in the Patients with Diabetes and Coronary Heart Disease

Implications of Magnesium Deficiency in Type 2 Diabetes: A Review

Magnesium Deficiency in Type 2 Diabetes

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