Diurnal Variations of Fibrinolytic Activity and Plasma-11-

Menon, I. S.; Smith, Pamela Alethea; White, Rebecca; Dewar, H. A.

doi:10.1016/s0140-6736(67)90495-3

Cited by 12 publications

(2 citation statements)

References 21 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In their work on dogs , however , Suzuki et al (1967) concluded that adrenal cortical secretion is not related to exercise. In an earlier study Menon et al (1967b) also failed to show any causal relationship between the increase in fibrinolytic activity and cortisol level. The present study takes the point further by showing a very small rise in the plasma cortisol level immediately after exercise but a significant decrease 1 hr later.…”

Section: Discussionmentioning

confidence: 81%

A Study of Possible Causes of Increased Fibrinolytic Activity during Exercise

Menon¹,

Burke²,

Smith³

et al. 1969

Thromb Haemost

View full text Add to dashboard Cite

SummaryThe prolonged effect in human volunteers of brief but moderately intense exercise in enhancing fibrinolytic activity has been used to test various parameters which might have been causatively associated with the change.HMMA, venous blood glucose, body temperature and diastolic blood pressure did not alter significantly at any time. The increase in pulse rate immediately after exercise did not correlate closely with the rise in fibrinolytic activity and disappeared much sooner.Plasma cortisol and systolic blood pressure had both fallen significantly 1 hr after exercise as compared to their preexercise levels, but there was no significant inverse relationship between these parameters and the changes in fibrinolytic activity.It is concluded that the parameters measured were unlikely to be responsible for the observed changes in fibrinolytic activity.

show abstract

Section: Discussionmentioning

confidence: 81%

A Study of Possible Causes of Increased Fibrinolytic Activity during Exercise

Menon¹,

Burke²,

Smith³

et al. 1969

Thromb Haemost

View full text Add to dashboard Cite

show abstract

“…This may be due to an excessive absolute increased concentration of plasminogen activator and/or a diminution in the physico-chemical binding mechanisms of the proposed antiactivatoractivator complex (Olesen, 1965). Menon, Smith, White and Dewar (1967) have shown that, at least in normal subjects, the more severe the exercise procedure the greater was the initial fibrinolytic response and the post-exercise recovery period. Thus it could be postulated that exaggerated initial response in some of the cirrhotic patients was simply reflecting an excessive degree of stress in those individuals.…”

Section: Discussionmentioning

confidence: 99%

Fibrinolysis at Rest and after Exercise in Hepatic Cirrhosis

Das

Cash

1969

Br J Haematol

View full text Add to dashboard Cite

Summary. A study of the fibrinolytic enzyme system in 37 cirrhotic patients at rest and 15 cirrhotic patients following a treadmill exercise procedure is reported. An outstanding feature of the resting studies was a significant elevation in the levels of plasma plasminogen activator and serum fibrin/fibrinogen degradation products, when compared to age and sex‐matched healthy controls. Moreover, there was a significant positive correlation between those two fibrinolytic parameters. No significant difference was demonstrated between the control and cirrhotic groups in relation to plasma fibrinogen, euglobulin plasminogen and plasma urokinase inhibitor activity. The exercise studies showed that following an entirely physiological stimulus the plasminogen activator response in some cirrhotics was excessive in terms of either the initial response and/or prolongation of the recovery period. However, an exaggerated initial response was not necessarily followed by a prolongation recovery period nor was a relationship established between the resting levels of plasminogen and an abnormal exercise response. Furthermore, there was no correlation between the increases in plasminogen activator and serum fibrin/ fibrinogen degradation products following exercise.

show abstract

Age, Sex, Circadian and Seasonal Variations in the Hemostatic Mechanism

Ogston

1983

The Physiology of Hemostasis

View full text Add to dashboard Cite

Diurnal Variations of Fibrinolytic Activity and Plasma-11-

Cited by 12 publications

References 21 publications

A Study of Possible Causes of Increased Fibrinolytic Activity during Exercise

A Study of Possible Causes of Increased Fibrinolytic Activity during Exercise

Fibrinolysis at Rest and after Exercise in Hepatic Cirrhosis

Age, Sex, Circadian and Seasonal Variations in the Hemostatic Mechanism

Contact Info

Product

Resources

About