2023
DOI: 10.1101/2023.07.04.547718
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Divergence in theSaccharomycesspecies’ heat shock response is indicative of their thermal tolerance

Abstract: The Saccharomyces species have diverged in their thermal growth profile. Both S. cerevisiae and S. paradoxus grow at temperatures well above the maximum growth temperature of S. kudriavzevii and S. uvarum, but grow more poorly at lower temperatures. In response to thermal shifts, organisms activate a stress response that includes heat shock proteins involved in protein homeostasis and acquisition of thermal tolerance. To determine whether Saccharomyces species have diverged in their response to temperature we … Show more

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“…However, since our study lacked feed intake data and other metrics pertinent to glucose metabolism, this hypothesis warrants further investigation in future research. Dietary TAN could be metabolized by microorganisms in the rumen, releasing phenolic compounds such as gallic acid, pyrogallol, and resorcinol [ 50 , 51 ], and excessive degradation products of TAN might exceed the detoxification capacity of the liver [ 52 ], leading to symptoms of toxicity in ruminants [ 53 ]. It is worth noting that the TAN added in our experiment had no adverse effects on the immune, inflammatory, and biochemical parameters (BUN, TC, TG, TP, and ALB) in the serum and liver of beef cattle.…”
Section: Discussionmentioning
confidence: 99%
“…However, since our study lacked feed intake data and other metrics pertinent to glucose metabolism, this hypothesis warrants further investigation in future research. Dietary TAN could be metabolized by microorganisms in the rumen, releasing phenolic compounds such as gallic acid, pyrogallol, and resorcinol [ 50 , 51 ], and excessive degradation products of TAN might exceed the detoxification capacity of the liver [ 52 ], leading to symptoms of toxicity in ruminants [ 53 ]. It is worth noting that the TAN added in our experiment had no adverse effects on the immune, inflammatory, and biochemical parameters (BUN, TC, TG, TP, and ALB) in the serum and liver of beef cattle.…”
Section: Discussionmentioning
confidence: 99%