Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines

Qu, Yifei; Cai, Xiaojia; Guan, Yuzhuang; Tan, Jiamin; Cai, Zhangping; Liu, Minyun; Huang, Yasi; Hu, Jinhui; Chen, Wen-Hua; Wu, Jia-Qiang

doi:10.1039/d3ob01735d

Org. Biomol. Chem.

2024

DOI: 10.1039/d3ob01735d

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Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines

Yifei Qu,

Xiaojia Cai,

Yuzhuang Guan

et al.

Abstract: A facile and straightforward method for the successful synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines by a Friedel–Crafts reaction is developed.

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One-pot sequential synthesis of unsymmetrical diarylmethanes using methylene chloride as a C1-synthon

Cui,

Chen,

Xie

et al. 2024

Org. Biomol. Chem.

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One-pot sequential synthesis of unsymmetrical diarylmethanes using methylene chloride as a C1-synthon

Cui,

Chen,

Xie

et al. 2024

Org. Biomol. Chem.

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show abstract

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Divergent synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines

Abstract: A facile and straightforward method for the successful synthesis of difluoromethylated indole-3-carbinols, bisindolylmethanes and indole-3-methanamines by a Friedel–Crafts reaction is developed.

Cited by 1 publication

References 43 publications

One-pot sequential synthesis of unsymmetrical diarylmethanes using methylene chloride as a C1-synthon

One-pot sequential synthesis of unsymmetrical diarylmethanes using methylene chloride as a C1-synthon

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