Diverse imaging findings of Lhermitte–Duclos disease

Lhermitte-Duclos disease in a 51-year old patient

“…Although tiger stripe appearance is highly specific, it has been observed in other lesions [13] . In addition, the absence of significant enhancement is characteristic of LDD, which suggests no significant blood-brain barrier damage and no extracellular edema [14] . However, enhancement has been reported [15] .…”

“…Moreover, a recent study suggested that tiger stripes tend to be present in cases of LDD accompanied by other CS neoplasms, while in cases where LDD is present alone, atypical radiological imaging is more common [14] .…”

“…LDD can exhibit variable diffusivity on DWI [14] . DWI and ADC images in our patient showed no diffusion restriction.…”

Lhermitte–Duclos disease: A systematic review

“…The finding that lesion enhancements and linear striations were observed in 14.9% and 58.7% of cases is consistent with a previous small-scale review of 21 patients that found that 61.9% of the patients manifested the classical layered pattern. [ 16 ] However, the tiger-stripe appearance is not unique to LDD, and it should be combined with other typical signs of LDD to enhance diagnosis. [ 16 ] Although MRI seems to have a reasonable level of specificity for LDD, recognizing that other lesions may mimic the MRI findings of LDD is important.…”

“…[ 16 ] However, the tiger-stripe appearance is not unique to LDD, and it should be combined with other typical signs of LDD to enhance diagnosis. [ 16 ] Although MRI seems to have a reasonable level of specificity for LDD, recognizing that other lesions may mimic the MRI findings of LDD is important. [ 8 , 21 ]…”