Diversity of Mechanisms for Boron Toxicity in Mammals

Rodríguez-Vera, Diana; Abad-García, Antonio; Barrón-González, Mónica; Segura-Uribe, Julia J.; Farfán‐García, Eunice D.; Soriano‐Ursúa, Marvin A.

doi:10.1201/9780429438004-32

Metal Toxicology Handbook 2020

DOI: 10.1201/9780429438004-32

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Diversity of Mechanisms for Boron Toxicity in Mammals

Diana Rodríguez-Vera¹,

Antonio Abad-García²,

Mónica Barrón-González³

et al.

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2024

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Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study

Mendoza‐Cano,

Ríos‐Silva,

Gonzalez-Curiel

et al. 2024

Sci Rep

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Environmental exposure to heavy metals and metalloids, originating from sources such as mining and manufacturing activities, has been linked to adverse renal effects. This cross-sectional study assessed children's exposure to these elements and its association with urinary kidney injury molecule-1 (KIM-1). We analyzed data from 99 school-aged children residing in nine localities within the state of Colima, Mexico, during the latter half of 2023. Levels of 23 metals/metalloids and urinary KIM-1 were measured using inductively coupled plasma mass spectrometry (ICP-MS) and enzyme-linked immunosorbent assay, respectively. Detectable levels of these contaminants were found in over 91% of participants, with varied exposure profiles observed across locations ($$p$$ p = 0.019). After adjusting for confounding factors like gender, age, and locality, higher levels of six metals/metalloids (boron, cadmium, cesium, lithium, selenium, zinc) were significantly associated with increased KIM-1 levels. Tailored mitigation efforts are crucial to protect children from regional pollutant burdens. However, limitations exist, as our study did not capture all potential factors influencing heavy metal/metalloid and KIM-1 levels.

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Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study

Mendoza‐Cano,

Ríos‐Silva,

Gonzalez-Curiel

et al. 2024

Sci Rep

View full text Add to dashboard Cite

show abstract

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Diversity of Mechanisms for Boron Toxicity in Mammals

Cited by 1 publication

References 1 publication

Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study

Metal concentrations and KIM-1 levels in school-aged children: a cross-sectional study

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