2015
DOI: 10.1007/s12038-015-9541-5
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Diversity of sickle cell trait in Jharkhand state in India: Is it the zone of contact between two geographically and ethnically distinct populations in India?

Abstract: Incidence of sickle cell trait in India is high in peninsular south, south-eastern, central and south-western India, while in north and north-eastern India, it is absent. Unicentric origin of SCD in the tribals of nilgiri hills in southern India has been proposed. The present study on the frequency of HbS trait and beta-globin gene haplotypes was conducted in the tribal-rich states of Chhattisgarh and Jharkhand to get an insight into the uneven distribution of HbS in India. Jharkhand borders with the HbS-high … Show more

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(3 citation statements)
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“…These are the most socioeconomically backward and disadvantaged population subgroups in the country. The average frequency of HbS trait is about 20% in Chhattisgarh, Maharashtra, Madhya Pradesh, Odisha and Gujarat in India (Nagar and Raman, 2015). In Odisha, SCD is a serious concern about health status of the state (Colah et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…These are the most socioeconomically backward and disadvantaged population subgroups in the country. The average frequency of HbS trait is about 20% in Chhattisgarh, Maharashtra, Madhya Pradesh, Odisha and Gujarat in India (Nagar and Raman, 2015). In Odisha, SCD is a serious concern about health status of the state (Colah et al, 2015).…”
Section: Introductionmentioning
confidence: 99%
“…Estimates indicate that sickle cell trait (SCT) is predominant among the tribal population of central India [2,3]. Incidence of SCD is 3.3% in tribal children of Chotanagpur (Jharkhand) which ranges from 0% to 10% in various parts of the state [4]. It is the melting pot of Arab Indian (AI) and East Asian (EA) haplotypes [4].…”
Section: Introductionmentioning
confidence: 99%
“…Incidence of SCD is 3.3% in tribal children of Chotanagpur (Jharkhand) which ranges from 0% to 10% in various parts of the state [4]. It is the melting pot of Arab Indian (AI) and East Asian (EA) haplotypes [4]. The predominant population of the newly formed state of Jharkhand, is tribal.…”
Section: Introductionmentioning
confidence: 99%