Diverticular bleeding — Are NSAIDS risk factors for hemorrhage and can colonoscopy predict outcome for patients?

Visceral fat accumulation affects risk of colonic diverticular hemorrhage

“…In addition, the number of cases with diverticular bleeding was relatively large compared with previous case-control studies involving smaller sample populations (<50 cases) [2,10,11,25,[30][31][32]. However, this study also has several limitations.…”

Lower gastrointestinal bleeding: a review

“…Approximately 20% of patients with diverticular bleeding have stigmata of definitive hemorrhage, 30% have presumed diverticular bleeding, and 50% have incidental diverticulosis with another definitive site [41]. The stigmata of significant hemorrhage seen at colonoscopy such as adherent clots, a nonbleeding visible vessel, or active bleeding have prognostic significance, and these patients are more likely to require transfusion and specific hemostatic therapy [26]. However, the majority of these patients, approximately 76%, stop bleeding spontaneously and do not require specific therapeutic intervention [8].…”

A guideline for the treatment and prevention of nsaid-induced ulcers

“…Another case-controlled study of patients with severe complications of diverticulosis showed that 48% of these patients were taking NSAIDs when compared with matched controls (p Ͻ 0.01) (117). More recently, in a retrospective review of 13 patients with unequivocal stigmata of recent diverticular hemorrhage, 12 (92%) were found to have been recently exposed to NSAIDs and/or aspirin (118).…”