Divorce and Severity of Coronary Artery Disease: A Multicenter Study

Daoulah, Amin; Al-Murayeh, Mushabab; Alkaabi, Salem; Lotfi, Amir; Elkhateeb, Osama; Al-Faifi, Salem M.; Alqahtani, Saleh; Stewart, James A.; Heavey, Jon; Hurley, William T.; Alama, Mohamed Nabil; Faden, Mazen; Al-Shehri, Mohamed A.; Youssef, Ali A.; Alsheikh‐Ali, Alawi A.

doi:10.1155/2017/4751249

Cited by 2 publications

(3 citation statements)

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“…We hypothesised that MPF would be associated with midlife obesity, given that it often involves an early age at first birth, high parity and multiple partnership dissolution—three factors that have been found to be independently associated to BMI as part of cardiovascular risk [ 8 , 9 , 11 , 26 , 63 – 65 ]. However, our study provides mixed support for this hypothesis.…”

Section: Discussionmentioning

confidence: 99%

Exploring the associations between number of children, multi-partner fertility and risk of obesity at midlife: Findings from the 1970 British Cohort Study (BCS70)

2023

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Background Early parenthood, high parity, and partnership separation are associated with obesity. However, the emergence of non-marital partnerships, serial partnering and childbearing across unions, means that it is important to consider their association to obesity. This paper examined the associations between number of biological children and multi-partner fertility (MPF)—defined as having biological children with more than one partner, with obesity at midlife. Method The sample consisted of 2940 fathers and 3369 mothers in the 1970 British Cohort Study. The outcome was obesity (BMI 30 or over) at age 46. Fertility and partnership histories ascertained the number of live biological children and MPF status by age 42. The associations were tested using logistic regression adjusting for confounders at birth, age 10 and age 16. Adult factors recorded at age 42 including age at first birth, smoking status, alcohol dependency, educational attainment and housing tenure were considered as mediators. Results For fathers, obesity odds did not differ according to number of children or MPF. In unadjusted models, mothers with one child (OR 1.24 95%CI 1.01–1.51), mothers who had two children with two partners (OR 1.45 95%CI 1.05–1.99), and mothers who had three or more children with two or more partners (OR 1.51 95%CI 1.18–1.93) had higher odds of obesity. In adjusted models, there remained an association between mothers with one child and odds of obesity (OR 1.30 95%CI 1.05–1.60). All other associations were attenuated when confounders were included. Conclusions Mothers who had children with multiple partners had higher odds of obesity. However this association was completely attenuated when parental and child confounders were accounted for; suggesting that this association may be explained by confounding. Mothers who had one child only may be at increased odds of obesity, however this could be due to multiple factors including age at first birth.

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Section: Discussionmentioning

confidence: 99%

Exploring the associations between number of children, multi-partner fertility and risk of obesity at midlife: Findings from the 1970 British Cohort Study (BCS70)

2023

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“…The Stepwise Psychotherapy Intervention for Reducing Risk in Coronary Artery Disease (SPIRR-CAD) trial, a multicenter study in Germany that studied patients with CAD and analyzed the social and economic status of the studied population, concluded that women with lower levels of education had less social and emotional support, while academic men had the most [40]. Following the practical implications of social status, specifically marital status, there is a meaningful influence on the severity of the condition in females; an observational, multicenter study reported that there is a significant association between divorce and severe multivessel disease, or left main disease, in women [41].…”

Section: Potential Biological and Sociocultural Factorsmentioning

confidence: 99%

“…(2017) [41] The observational, multicenter study focused on establishing the relationship between divorce and the severity of CAD, MVD, and LMD in men and women.…”

Section: Dreyer Et Al (2015) [39]mentioning

confidence: 99%

The Influence of Sex, Age, and Race on Coronary Artery Disease: A Narrative Review

Lima Dos Santos,

Matharoo,

Pinzón Cueva

et al. 2023

Cureus

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Cardiovascular disease has remained one of the leading causes of mortality in the world. The basic pathophysiology of coronary artery disease (CAD) is a reduction of the blood flow in coronary vessels, leading to restricted blood flow to the heart muscle. Both modifiable and non-modifiable risk factors contribute to its multifactorial etiology. The clinical presentation ranges from asymptomatic to typical symptoms like chest pain, shortness of breath, and left arm or jaw pain. The purpose of this review is to investigate and analyze the variation of CAD depending on the biological sex, age, race, or ethnicity and how it might differ in the studied population while comparing the symptoms and prognosis of CAD.For this research, PubMed's database was used. A total of 926 articles were selected using pre-determined inclusion and exclusion criteria, with 74 articles eligible to be included in the narrative review. Studies were selected from the general population of patients with CAD, regardless of their severity, stage of diagnosis, and treatment plan. The scale for the assessment of non-systematic review articles (SANRA) was used to assess the quality of the study.As humans age, the incidence of CAD increases, and people over 75 are more likely to have multiple-vessel CAD. It has been observed that South Asians have the highest rate of CAD at 24%, while the White population has the lowest at 8%. The prevalence of CAD also depends on race, with the White population having the lowest rate at 3.2%, followed by Hispanics at 5%, Black women at 5.2%, and Black men at 5.7%. Younger Black women tend to have more chest pain. Men with CAD commonly experience chest pain, and women are more likely to present with atypical symptoms. Modifiable risk factors such as smoking and alcoholism are more commonly observed in young men than in young women.Coronary artery disease in the elderly, female, minority, and Black patients is associated with a higher mortality rate. Acknowledging the prevalence of certain risk factors, signs, results, and responses to treatment in certain socio-demographic groups, as well as the provision and accessibility of diagnosis and treatment, would lead to a better outcome for all individuals. The impact of this shift can range from an earlier diagnosis of CAD to a faster and more customized treatment plan tailored to each patient's individual requirements.

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Divorce and Severity of Coronary Artery Disease: A Multicenter Study

Cited by 2 publications

References 39 publications

Exploring the associations between number of children, multi-partner fertility and risk of obesity at midlife: Findings from the 1970 British Cohort Study (BCS70)

Exploring the associations between number of children, multi-partner fertility and risk of obesity at midlife: Findings from the 1970 British Cohort Study (BCS70)

The Influence of Sex, Age, and Race on Coronary Artery Disease: A Narrative Review

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