Djenkol bean poisoning (Djenkolism): An unusual cause of acute renal failure

Segasothy, M; Swaminathan, Madhav; Kong, Norella; Bennett, William M.

doi:10.1016/0272-6386(95)90627-4

Cited by 29 publications

(21 citation statements)

References 1 publication

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“…91 A single case of djenkolism in an adult has also been reported. 93 Renal biopsy in this patient showed changes similar to those found in the animal studies. Djenkolic acid, extracted from beans, has been determined using paper chromatography.…”

Section: Pithecolobium Lobatumsupporting

confidence: 83%

Nephrotoxicity Associated With Exposure to Plant Toxins, With Particular Reference to Africa

Steenkamp

Stewart²

2005

Therapeutic Drug Monitoring

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Acute renal failure is a frequent cause of morbidity and mortality in the hospitalized population worldwide. In Africa, apart from hemodynamic causes and infections, herbal remedies contribute to both morbidity and mortality, although these causes often go unrecognized. This paper reviews reports of herbal remedies that have been shown to result in nephrotoxicity. The indications for use of the remedies, signs and symptoms in poisoned patients, and the methods used to detect toxic compounds in plant specimens or in biological fluids are covered.

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Section: Pithecolobium Lobatumsupporting

confidence: 83%

Nephrotoxicity Associated With Exposure to Plant Toxins, With Particular Reference to Africa

Steenkamp

Stewart²

2005

Therapeutic Drug Monitoring

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show abstract

“…Acute tubular ne- crosis, Acute renal failure, nephropathy, tubular necrosis, acute interstitial nephritis are serious complications resulting from the use of herbs like Pithecellobium labatum, Aristolochia fangchi, Uncaria tomentosa. [10][11][12][13][14] Therefore, the present investigation has been conducted to understand the biochemical and histopathological alterations associated with acute oral toxicity of aqueous leaf extract of P. niruri. Acute toxicity (LD 50 ) test gives a clue on the range of doses that could be used in subsequent toxicity for testing and estimating the therapeutic index of drugs and xenobiotics.…”

Section: Discussionmentioning

confidence: 99%

Acute toxicity study of Phyllanthus niruri and its effect on the cyto-architectural structure of nephrocytes in Swiss albino mice Mus-musculus

Singh¹,

Ruchi²,

Singh³

et al. 2015

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“…The jering poisoning or djenkolism is characterized by spasmodic pain, urinary obstruction, and acute kidney injury. 36 The underlying pathologic process is an obstructive uropathy. On a more chronic basis, djenkol bean consumption is associated with a fourfold higher risk of nonglomerular hematuria.…”

Section: Acute Kidney Injurymentioning

confidence: 99%