DMSO coordinated dioxidomolybdenum(VI) complexes chelated with 3-methoxybenzhydrazone related ligands: Synthesis, structural studies and in vitro cytotoxicity

Crystal structure of (N,N-dimethylsulphoxide)-[N-(3-ethoxy-2-(oxide)benzylidene)-3-methoxybenzenecarbohydrazonato-κ3N,O,O′]-dioxo-molybdenum(VI), C19H22MoN2O7S

“…The most closely related structure in the literature is of the analogue where the ethoxy substituent of (I) is methoxy [8]. As would be anticipated, the same trends in geometric parameters are evident.…”

“…It is now well established that the sixth coordination site in mononuclear dioxidomolybdenum(VI) complexes of ONOdonor Schiff base dianions is labile [5][6][7][8], with exchange between different molecules, e.g. solvent, often observed.…”

“…solvent, often observed. Further interest in these molecules arises as a result of investigations of putative anti-cancer potential [6,8]. In continuation of structural studies of Mo complexes of Schiff bases [6,9,10], the title complex, (I), with a coordinated DMSO molecule, was investigated crystallographically with a further analysis of the molecular packing performed through the calculated Hirshfeld surfaces.…”

Syntheses, Crystal Structures and Catalytic Property of Oxidovanadium(V) Complexes Derived from Tridentate Hydrazone Ligands

“…2f,4e,13 The bond lengths of C8-O2 (1.31 Å) indicate they are more close to single bonds, which is due to the conjugation effects of the ligands. 14 In addition, the bond lengths of C8-N2 (1.30 Å) and N1-N2 (1.40 Å) are intermediate between single and double bonds, which also supports the electron cloud delocalization in the hydrazone ligands. The five-membered chelate rings (V1-N1-N2-C8-O2) are nearly planar, while the six-membered chelate rings (V1-O1-C2-C1-C7-N1) are obviously distorted from planarity.…”

Novel dioxidomolybdenum complexes containing ONO chelators: Synthesis, physicochemical properties, crystal structures, Hirshfeld surface analysis, DNA binding/cleavage studies, docking, and in vitro cytotoxicity

“…In the advancement of the coordination chemistry of molybdenum, aroylhydrazones play a crucial role as these tridentate ligands coordinated with molybdenum is greatly similar to the active sites of most of the molybdoenzymes. [ 6 ] The physical and chemical properties of hydrazones are determined by the azomethine group characterized by the triatomic structure (–C=N–N–). [ 7 ] Moreover, these structural motifs display configurational isomerism due to the inherent nature of the imine group.…”