DNA-binding and cleavage studies of macrocyclic copper(II) complexes

Synthesis, characterization, antioxidant, antimicrobial, DNA binding and cleavage studies of mononuclear Cu(II) and Co(II) complexes of 3-hydroxy-N'-(2-hydroxybenzylidene)-2-naphthohydrazide

“…A similar hyperchromism was also observed for a copper(II) complex with a ligand bearing -OH group [44]. As DNA double helix possesses many hydrogen bonding sites which are accessible both in the minor and in the major grooves, it is likely that the -OH group of the ternary complex forms hydrogen bonds with DNA, which may contribute to the hyperchromism observed in absorption spectra.…”

Refinement of the 12q14 microdeletion syndrome: primordial dwarfism and developmental delay with or without osteopoikilosis

“…TMBIM4 stands for transmembrane BAX inhibitor motif containing protein 4; it is also known as S1R, and its function is unknown. CAND1 or TBP-interacting protein seems to be a ubiquitine ligase complex regulator 6 . GRIP1 encodes a protein that contains a PDZ domain, important for synaptic function, 7 and that is highly expressed in both fetal and adult brain.…”

The interaction of native DNA with iron(III)-N,N′-ethylene-bis(salicylideneiminato)-chloride

“…There is in fact a small increase in the relative viscosity of DNA by increasing the concentration of the Fe(Salen) þ complex. It has been reported [38][39][40][41][42][43] that a compound binding to DNA without intercalation, induces only small changes in the viscosity of DNA, while drastic increments of the viscosity were observed in cases of ascertained DNA intercalation by chemicals. Moreover, the results obtained show that the observed small linear increase of the relative viscosity of the solution, with the increase of the Fe(Salen)Cl concentration, is essentially attributable to the addition of the methanol solvent [44] in which Fe(Salen)Cl is dissolved.…”