2024
DOI: 10.5507/bp.2023.044
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DNA damage and arterial hypertension. A systematic review and meta-analysis

Radka Hazukova,
Martina Rezacova,
Miloslav Pleskot
et al.

Abstract: Oxidative DNA damage markers (8OHdG, comet assay, gammaH2AX) are becoming widely used in clinical cardiology research. To conduct this review of DNA damage in relation to hypertension in humans, we used databases (e.g. PubMed, Web of Science) to search for English-language publications up to June 30, 2022 and the terms: DNA damage, comet assay, gammaH2AX, 8OHdG, strand breaks, and arterial hypertension. Exclusion criteria were: children, absence of relevant controls, extra-arterial hypertensive issues, animal,… Show more

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