2023
DOI: 10.20944/preprints202309.1932.v1
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DNA damage response & senescence-associated secretory phenotype pathway: Emerging targets for anti-aging

Jawad Nadeem,
Amna Parveen,
Sun Yeou Kim

Abstract: Cellular aging has drawn the attention of researchers, scientists, and biotech businesses for the treatment of a number of medical conditions. Cellular aging is primarily defined by consistent cessation of proliferative development in response to internal and external stressors, including DNA damage, telomere shortening, mitochondrial dysfunction, and regulation of the senescence-associated secretory phenotype (SASP). Disturbances involving these factors may contribute to age-related disease development. There… Show more

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