Modern Integrated circuits (ICs) suffer from excessive power and temperature issues because of embedding a large number of applications on small silicon real estate. Low power technique is introduced to reduce the power. With the reduction of power, area of circuit increases and vice versa. It shows a trade-off nature between them. Increase of area is against the trend of technology scaling which demands small area. Due to small area and high power dissipation, power-density increases. As power-density is directly converging into temperature, it emerges as a challenge in front of the VLSI design engineer to minimize the effect of temperature by reducing power-density. In this work, an attempt has been made to reduce the effect of powerdensity along with area and power so that AND-XOR based circuit is balanced in terms of area, power, and temperature. AND-XOR based reed-muller (RM) mixed polarity circuit forms are considered in this work. Polarity conversions are made in such a way that possibility of maximum sharing among the sub-function is increased. Genetic algorithm is (a non-exhaustive heuristic algorithm) used to select the polarity of the input variable for maximum sharing. The proposed synthesis approach shows 27.11%, 20.69%, and 32.30% savings in area, power, and power-density respectively than that of reported results. For the validation of the proposed approach, the best solutions are implemented in Cadence digital domain to obtain actual silicon area and power consumption. HotSpot tool is used to get the absolute temperature of the circuit.Spreader thickness = 1mm, Chip to spreader interface thickness = 0.020mm, Dynamic temperature management = above 85 °C .