DNA methylation profile of a rural cohort exposed to early-adversity and malnutrition: An exploratory analysis

Gómez-Verján, Juan Carlos; Esparza-Aguilar, Marcelino; Martín-Martín, Verónica; Salazar-Pérez, Cecilia; Cadena-Trejo, Cinthya; Gutiérrez‐Robledo, Luis Miguel; Arroyo, Pedro

doi:10.1016/j.exger.2022.111899

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“…Children with these pathologies may bear some sociomedical burden in the future. Thus, according to the report of Tafese et al (1) and recent studies describing the importance of nutritional interaction between children and mothers (2,3) , food insecurity and child undernutrition in rural areas are being increasingly recognised as serious issues. A greater understanding by both the public and governments concerning the present situation is needed in order to address this issue.…”

Section: To the Editormentioning

confidence: 99%

“…The second viewpoint is the epigenetic effect of malnutrition in pregnancy and childhood on later life stages (3) . The finding of a recent research in a rural cohort population (3) indicated that the most strongly affected methylated regions were those significantly related to the pathways involved in reproductive behaviours, neuronal systems, and learning and memory regulation (3) . Children with these pathologies may bear some sociomedical burden in the future.…”

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confidence: 99%

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