DNA-programmed self-assembly of photonic nanoarchitectures

Lan, Xiang; Wang, Qiangbin

doi:10.1038/am.2014.16

Cited by 30 publications

(26 citation statements)

References 79 publications

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“…To assemble NPs in a facile and precise manner, DNA molecules work well as a template . For instance, a long single‐stranded (ss) DNA template (more than 10 000 bases) comprised of a short repeating sequence is useful for aligning a large number of NPs monofunctionalized with a short ssDNA .…”

Section: Introductionmentioning

confidence: 99%

“…To assemble NPs in a facile and precise manner, DNA molecules work well as a template. [5][6][7][8][9][10] For instance, a long single-stranded (ss) DNA template (more than 10 000 bases) comprised of a short repeating sequence is useful for aligning a large number of NPs monofunctionalized with a short ssDNA. [11][12][13] The repeating sequence of the template is designed to be complementary to the sequence of the short ssDNA tethered to the NP surface.…”

Section: Introductionmentioning

confidence: 99%

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Modulation of Interparticle Distance in Discrete Gold Nanoparticle Dimers and Trimers by DNA Single‐Base Pairing

Akiyama

Shikagawa

Kanayama

et al. 2015

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Self-assembled structures of metallic nanoparticles with dynamically changeable interparticle distance hold promise for the regulation of collective physical properties. This paper describes gold nanoparticle dimers and trimers that exhibit spontaneous and reversible changes in interparticle distance. To exploit this property, a gold nanoparticle is modified with precisely one long DNA strand and approximately five short DNA strands. The long DNA serves to align the nanoparticles on a template DNA via hybridization, while the short DNAs function to induce the interparticle distance changes. The obtained dimer and trimer are characterized with gel electrophoresis, dynamic light scattering measurements, and transmission electron microscopy (TEM). When the complementary short DNA is added to form the fully matched duplexes on the particle surface in the presence of MgCl2 , spontaneous reduction of the interparticle distance is observed with TEM and cryo-electron microscopy. By contrast, when the terminal-mismatched DNA is added, no structural change occurs under the same conditions. Therefore, the single base pairing/unpairing at the outermost surface of the nanoparticle impacts the interparticle distance. This unique feature could be applied to the regulation of structures and properties of various DNA-functionalized nanoparticle assemblies.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Modulation of Interparticle Distance in Discrete Gold Nanoparticle Dimers and Trimers by DNA Single‐Base Pairing

Akiyama

Shikagawa

Kanayama

et al. 2015

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“…[1][2][3][4][5][6][7][8] In a different line, DNA-AuNP conjugates hold great promise as the building blocks for bottom-up construction of functional nanosystems that exploits both the highly specific DNA base-pair interactions and the unique optical and electronic properties of AuNPs. [9][10][11][12][13] During the past two decades, we have witnessed dramatic advances in such functional nanosystems, including the formation of molecule-like crystal structures and the assembly of dynamic nanodevices. [14][15][16][17][18] Despite the rapid progress, most of these applications used polyvalent DNA-AuNP conjugates without knowing the exact number of loaded DNA strands.…”

Section: Introductionmentioning

confidence: 99%

Clicking DNA to gold nanoparticles: poly-adenine-mediated formation of monovalent DNA-gold nanoparticle conjugates with nearly quantitative yield

et al. 2015

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Monovalent DNA-gold nanoparticle (mDNA-AuNP) conjugates hold great promise for widespread applications, especially the construction of well-defined, molecule-like nanosystems. Previously reported methods all rely on the use of thiolated DNA to functionalize AuNPs, resulting in relatively low yields. Here, we report a facile method to rapidly prepare mDNA-AuNPs using a poly-adenine (polyA)-mediated approach. As polyA can selectively bind to AuNPs with high controllability of the surface density of DNA, we can use a DNA strand with a sufficiently long polyA to wrap around the surface of an individual AuNP, preventing further the adsorption of additional strands. Based on this observation, we obtained mDNA-AuNPs with a nearly quantitative yield of~90% using 80 As, as confirmed by both gel electrophoresis and transmission electron microscope observation. The yields of mDNA-AuNPs were insensitive to the stoichiometric ratio between DNA and AuNPs, suggesting the click chemistry-like nature of this polyA-mediated reaction. mDNA-AuNPs exhibited rapid kinetics and high efficiency for sequence-specific hybridization. More importantly, we demonstrated that AuNPs of fixed valences could form well-defined heterogenous oligomeric nanostructures with precise, atom-like control.

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“…Self‐assembly of extremely well‐defined artificial DNA nanostructures has developed into a very powerful tool with promising biomedical and photonic applications . Utilizing the Watson–Crick base pairing mechanism and the interconnection by Holliday junctions, the robust DNA origami technique allows the formation of arbitrary 2D and 3D nanostructures .…”

Section: Introductionmentioning

confidence: 99%

Alignment and Graphene-Assisted Decoration of Lyotropic Chromonic Liquid Crystals Containing DNA Origami Nanostructures

Martens

Funck

Kempter

et al. 2016

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Utilizing the Watson-Crick base pairing mechanism [ 23 ] and the interconnection by Holliday junctions, [ 24,25 ] the robust DNA origami technique allows the formation of arbitrary 2D [ 4 ] and 3D nanostructures. [5][6][7][8][9][10][11][12][13][14][15][16][17] Functionalization of these nanostructures with biomolecules, fl uorophores, metal nanoparticles, or semiconductor quantum dots opens interesting opportunities for biomedical applications, [ 18,19 ] analytics and microscopy, [ 26,27 ] nanoelectronics, [ 28 ] or nanoplasmonics and nanophotonics. [19][20][21][22][29][30][31][32][33][34] However, not only isotropic aqueous dispersions or surfaces containing well-defi ned nanoobjects, [ 35 ] but also bulk materials may be targeted, where these objects exhibit a well-defi ned orientation or are arranged in an array with well-defi ned positions. For this purpose, self-organization on a micrometer scale or mesoscale would be very useful. Liquid crystals (LCs), ordered fl uids, are ideal candidates for bridging the gap between ordering on the sub-µm and µm length scales. LCs show a collective behavior of anisometric molecules or molecular aggregates: the resulting phenomena, like elastic behavior, surface alignment, or interaction with external electric and magnetic fi elds are described by characteristic lengths, which are typically in the µm range.[ 36 ] This is not only important for fl at panel displays, where LC fi lms with a thickness of a few µm are realigned by electric fi elds, but can also be used to control the alignment of rod-like or disk-like nanoparticles, for example, gold or semiconductor nanorods, carbon nanotubes,

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DNA-programmed self-assembly of photonic nanoarchitectures

Cited by 30 publications

References 79 publications

Modulation of Interparticle Distance in Discrete Gold Nanoparticle Dimers and Trimers by DNA Single‐Base Pairing

Modulation of Interparticle Distance in Discrete Gold Nanoparticle Dimers and Trimers by DNA Single‐Base Pairing

Clicking DNA to gold nanoparticles: poly-adenine-mediated formation of monovalent DNA-gold nanoparticle conjugates with nearly quantitative yield

Alignment and Graphene-Assisted Decoration of Lyotropic Chromonic Liquid Crystals Containing DNA Origami Nanostructures

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