1989
DOI: 10.1016/0921-8777(89)90018-9
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DNA repair mechanisms affecting cytotoxicity by streptozotocin in E. coli

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1990
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Cited by 11 publications
(2 citation statements)
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“…Indeed, 3-methyl-2/-deoxyadenosine (3-Me-dAdo) seems largely responsible for the toxicity associated with exposure to cytotoxic methylating agents (127). Bacteria deficient in the repair of this lesion are exquisitely sensitive to killing by monofunctional alkylating agents, whereas transfection with plasmids expressing repair enzymes restores normal sensitivity to such agents (128)(129)(130). As to be an SOS-dependent premutagenic lesion in repairdeficient bacteria (131).…”
mentioning
confidence: 99%
“…Indeed, 3-methyl-2/-deoxyadenosine (3-Me-dAdo) seems largely responsible for the toxicity associated with exposure to cytotoxic methylating agents (127). Bacteria deficient in the repair of this lesion are exquisitely sensitive to killing by monofunctional alkylating agents, whereas transfection with plasmids expressing repair enzymes restores normal sensitivity to such agents (128)(129)(130). As to be an SOS-dependent premutagenic lesion in repairdeficient bacteria (131).…”
mentioning
confidence: 99%
“…This cluster was found to be the basic theme in this time period. A typical representative article for this cluster is the article published by Fram et al with the title "DNA repair mechanisms affecting cytotoxicity by streptozotocin in E. coli" [31]. A further important basic research time in this period was also encompassed in the cluster "Transcription, Genetic/ drug effects" consisting of the MeSH headings relating to the gene expression and regulation of gene expression and drug effects on the gene expression and regulation of this expression.…”
Section: Period 1981-1990mentioning
confidence: 99%