DNA sensing technology a useful food scanning tool

Melinte, Gheorghe; Hosu, Oana; Cristea, Cécilia; Marrazza, Giovanna

doi:10.1016/j.trac.2022.116679

Cited by 22 publications

(12 citation statements)

References 219 publications

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“…The increase of emissions of fluorescence polarization of a fluorescence-labelled patulin derivative, which binds to particular antibodies, is characterized. The LODs for the patulin ranges from 6 to 102 µg/L due to competition between the patulin and the fluorescence-labelled patulin derivative ( Melinte et al., 2022 ). The proposed technique was based on the unique properties of crystal or quartz materials.…”

Section: Detection Technology Of Patulin and Alternaria ...mentioning

confidence: 99%

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Bacha

Nie

et al. 2023

Front. Plant Sci.

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Mycotoxins are toxic secondary metabolites produced by certain fungi, which can contaminate various food commodities, including fruits and their derived products. Patulin and Alternaria toxins are among the most commonly encountered mycotoxins in fruit and their derived products. In this review, the sources, toxicity, and regulations related to these mycotoxins, as well as their detection and mitigation strategies are widely discussed. Patulin is a mycotoxin produced mainly by the fungal genera Penicillium, Aspergillus, and Byssochlamys. Alternaria toxins, produced by fungi in the Alternaria genus, are another common group of mycotoxins found in fruits and fruit products. The most prevalent Alternaria toxins are alternariol (AOH) and alternariol monomethyl ether (AME). These mycotoxins are of concern due to their potential negative effects on human health. Ingesting fruits contaminated with these mycotoxins can cause acute and chronic health problems. Detection of patulin and Alternaria toxins in fruit and their derived products can be challenging due to their low concentrations and the complexity of the food matrices. Common analytical methods, good agricultural practices, and contamination monitoring of these mycotoxins are important for safe consumption of fruits and derived products. And Future research will continue to explore new methods for detecting and managing these mycotoxins, with the ultimate goal of ensuring the safety and quality of fruits and derived product supply.

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Section: Detection Technology Of Patulin and Alternaria ...mentioning

confidence: 99%

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Bacha

Nie

et al. 2023

Front. Plant Sci.

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“…The sensor configuration enabled the detection of S- and N-proteins in untreated saliva as low as ng/mL, within 30 min [ 139 ]. One of the recent strategies for DNA amplification is represented by the isothermal technique named rolling circle amplification (RCA) [ 149 ]. A voltammetric biosensor that used the RCA amplification for the simultaneous detection of S- and N-genes of SARS-CoV-2 in nasopharyngeal and throat swab was developed by Chaibun et al [ 140 ].…”

Section: Biomarkers Involved In Inflammatory Diseasesmentioning

confidence: 99%

“…Taking into account that none of the presented devices are commercially available and are not in clinical trials, we included in the “Fully” category all the devices that meet the ASSURED criteria except for the last one, namely to be “Deliverable to all people need.” Also, it can be observed that most of the detection devices presented do not meet the “Equipment-free” criterion, and this shortcoming is due to the operation mode of the electrochemical sensors and biosensors, which require the presence of a potentiostat and implicitly an energy source. In several studies from the examples presented, it was possible to solve this shortcoming by developing miniaturized, portable, and ultraportable potentiostats, accessible in terms of price and which allow the operation of the elaborated sensors in a decentralized manner [ 36 , 42 , 71 , 98 , 104 , 128 – 130 , 136 , 137 , 139 , 141 , 144 , 146 , 147 , 149 , 152 , 158 , 159 ]. In addition, taking into account the special progress in the field of electronics in recent years, we are confident that this shortcoming will be overcome very soon, especially if the advantages that accompany electrochemical detection systems are considered.…”

Section: Conclusion Future Perspectives and Challengesmentioning

confidence: 99%

Point-of-care electrochemical testing of biomarkers involved in inflammatory and inflammatory-associated medical conditions

et al. 2022

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Recent years have shown that the diagnosis and monitoring of biomarkers involved in inflammatory-associated medical conditions such as cancer, neurological disorders, viral infections, or daily physical activities offer real benefits in increasing the quality of medical care and patient life quality. In this context, the use of integrated and portable platforms as point-of-care testing devices for biomedical analysis to enable early disease diagnosis and monitoring, which can be successfully used even at the patient’s bed, is an emergency nowadays. The development of low-cost, miniaturized, and portable, user-friendly devices that provide an answer in a timely manner, such as electrochemical sensors, is relevant for the elaboration of point-of-care testing devices. This review focuses on the recent progress in bioanalysis of both specific biomarkers and inflammatory-associated biomarkers present in several diseases like neoplasia, severe neurological disorders, viral infections, and usual physical activity and provides an overview of the state of the art over the most recent electrochemical (bio)sensors for the detection of inflammation-related biomarkers. Future perspectives of point-of-care testing to improve healthcare management are also discussed. Graphical abstract

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“…Compared with nucleic acid detection technologies based on DNA amplication, an electrochemical DNA biosensor is widely preferred for nucleic acid detection because of its higher sensitivity, non-enzymatic process, and easy operation. [6][7][8][9][10][11][12][13][14][15][16] At present, most electrochemical DNA biosensors need the DNA probes to be immobilized on the electrode, and the generated signal is based on the change in DNA conformation aer hybridization on the electrode surface. [17][18][19] However, the immobilization of the probe commonly takes a long time, which prolongs the overall detection time and further limits the application of the probe-immobilized electrochemical DNA biosensors.…”

Section: Introductionmentioning

confidence: 99%

“…Compared with nucleic acid detection technologies based on DNA amplification, an electrochemical DNA biosensor is widely preferred for nucleic acid detection because of its higher sensitivity, non-enzymatic process, and easy operation. 6–16…”

Section: Introductionmentioning

confidence: 99%

A homogeneous hybridization magnetic biosensor based on electric field assistance for ultrafast nucleic acid detection

Cui¹,

Sun²,

Zhao³

et al. 2023

Anal. Methods

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DNA sensing technology a useful food scanning tool

Cited by 22 publications

References 219 publications

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Comprehensive review on patulin and Alternaria toxins in fruit and derived products

Point-of-care electrochemical testing of biomarkers involved in inflammatory and inflammatory-associated medical conditions

A homogeneous hybridization magnetic biosensor based on electric field assistance for ultrafast nucleic acid detection

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