DNA sequencing of HLA-B alleles in Mexican patients with Takayasu arteritis

Takayasu arteritis: a review

“…[21][22][23] For example, in Japan and Korea there is a clear association with the extended haplotype: HLA B*52, DRB1*1502, DRB5*0102, DQA1*0103, DQB1*0601, DPA1*02-DPB1*0901. 21 Sequence analysis has shown that some of the alleles share specific epitopes and it may be that the epitopes are more important as a disease susceptibility factor than the allele in which they are found.…”

Takayasu arteritis in a child: A case report

“…Alarcón et al demostraron HLA B*15, B*39 y B*40 en (14) la mayoría de sus pacientes mexicanos . Sin embargo, Salazar et al describen presencia de HLA-DRB1*1602 and HLA-DRB1*1001 en una población (15) colombiana .…”

Comparative study of the residues 63 and 67 on the HLA‐B molecule in patients with Takayasu's arteritis and tuberculosis

“…[7][8][9] Specific residues in the HLA molecule could also confer genetic susceptibility to TB, because several HLA alleles have been found to be associated with the disease in different populations. Therefore, the similar clinical features that TA and TB present could be better explained by the effect of a specific sequence rather than the effect of a specific allele.…”

“…2,7 Sequencing of HLA-B alleles in Mexican patients showed that these alleles share residues with Asian alleles (-B51, -B52, and -B39) associated with the disease. 8,9 On the other hand, a possible relationship between TA and tuberculosis (TB) has been proposed because of the similarities of the chronic inflammatory lesions in both diseases, as well as, in some cases, occlusive lesions on arterial walls in some examples of advanced pulmonary TB. [10][11][12] In addition, the rare coexistence of TA with pulmonary or extrapulmonary TB, the high frequency of skin delayed hypersensitivity to mycobacterial antigens in the form of purified protein derived (PPD) and a single case of improvement of TA when TB has been successfully treated, [13][14][15][16] suggest a possible link between these diseases.…”