DNAzyme self-assembled gold nanorods-based FRET or polarization assay for ultrasensitive and selective detection of copper(II) ion

He, Youwei; Tian, Jianniao; Zhang, Juanni; Chen, Sheng; Jiang, Yixuan; Hu, Kun; Zhao, Yi; Zhao, Shulin

doi:10.1016/j.bios.2013.12.032

Cited by 54 publications

(19 citation statements)

References 24 publications

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“…Similarly, rod-shaped AuNPs coated with positively charged surfactants acted as binders and quenchers for fluorophore-labeled 8–17 DNAzymes and substrates [86], allowing the detection of Pb 2+ by fluorescence enhancement (Figure 1B). Another study used a similar design for Cu 2+ detection using a Cu 2+ -dependent DNA-cleaving DNAzyme via a AuNP-based FRET assay [87]. Xie et al [88] developed a triple-channel optical signal (fluorometric, colorimetric, and resonance light scattering) probe for the detection of Hg 2+ (Figure 1C), based on the different interactions of AuNPs with single-stranded DNA (ssDNA) and double-stranded DNA (dsDNA), the high binding affinity of positively charged acridine orange dye for DNA, and the modulation of the efficiency of energy transfer between fluorescent dyes and AuNPs.…”

Section: Noble Metal Nanomaterials-based Fluorescent Nanoprobes Fomentioning

confidence: 99%

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

et al. 2016

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Summary Recent advances in nanoscale science and technology have generated nanomaterials with unique optical properties. Over the past decade, numerous fluorescent nanoprobes have been developed for highly sensitive and selective sensing and imaging of metal ions, both in vitro and in vivo. In this review, we provide an overview of the recent development of the design and optical properties of the different classes of fluorescent nanoprobes based on noble metal nanomaterials, upconversion nanoparticles, semiconductor quantum dots, and carbon-based nanomaterials. We further detail their application in the detection and quantification of metal ions for environmental monitoring, food safety, medical diagnostics, as well as their use in biomedical imaging in living cells and animals.

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Section: Noble Metal Nanomaterials-based Fluorescent Nanoprobes Fomentioning

confidence: 99%

Fluorescent nanoprobes for sensing and imaging of metal ions: Recent advances and future perspectives

et al. 2016

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“…Moreover, the design of DNA molecules mainly depends on the capacity of the metal ions to form steady metal-DNA duplexes. Therefore, DNAzymes and DNA molecules have been converted into various sensors with some advantages of satisfactory specificity, stability and sensitivity for the potential application in ion detection [156][157][158][159].…”

Section: Fluorescence-based Ion Sensing (I) Dnazyme/dna Molecules-functionalized Ion Sensingmentioning

confidence: 99%

Emerging barcode particles for multiplex bioassays

Wang

Chen

et al. 2018

Sci. China Mater.

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With the increasing demand for multiplex and high-throughput analysis of large numbers of biomolecules, multiplex technology becomes a promising tool for carrying out thousands of individual reactions at the same time for large-scale biological analysis. Among current technologies, suspension arrays based on appropriate barcode particles have been popularly used in multiplex bioassays of many research fields with the ability of unique encoding, such as in the clinical, medicinal, nutritional, and environmental fields. Besides the unique form of barcode, these particles have higher flexibility, better sensitivity, and faster reaction kinetics. In this review, we present some examples of typical barcode particles that are divided into different groups depending on how they are encoded and their applications in multiplex bioassays for different targets such as proteins, DNA and RNA sequences, and cells. The bioassays for monitoring food safety, drug research, and clinical diagnosis are also described.

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“…The biorecognition element of the sensor is formed of DNA enzymes, in which one of the (enzyme) strands catalyzes the breaking of its complementary (substrate) stand upon analyte detection. 8 We LIFT-printed well-shaped round micropatterns of the DNA enzymes onto silane-functionalized silicon-nitride surfaces. The printing was carried out by projecting the beam of a neodymium-doped yttrium-aluminum-garnet laser (with a 355nm wavelength, 10ns pulse duration, and projected area of 50 m 2 ) onto the donor substrate.…”

Section: 1117/21201605006410 Page 2/3mentioning

confidence: 99%