Background: Saudi Arabia has faced a steady growth in the prevalence of obesity. Implementation of Mobile health (mHealth) technology as a method of delivering behavioral interventions may be effective in lifestyle and diet modification. Despite this, there are few weight-loss apps available and a lack of robust interventions from the Gulf region. Objective: The current study examines the discourse between evidence requirements, user expectations and experiences. Methods: Usability of the Twazon app was evaluated by analyzing user opinions and experiences from participants of an app-based weight-loss intervention; this was completed using a System Usability Scale and Word Clouds. The results were triangulated with those obtained in a focus group discussion with potential users' expectations and an Arabic app screening for evidence-based practices. Results: The Twazon app was found to be 'more than satisfactory' with an average reported SUS score of 69.3. The most favored features were the calorie counter, step counter and physical activity calorie counter. The features in need of improvement were the social network, notifications, and the Saudi food database; a barcode feature was also recommended. Twazon users preferred and found the utility of seven of the thirteen evidence-informed weight-loss practices that were integrated into the features of the app. Conclusions: Triangulation identified the greatest discourse between user experience and two of the evidence-informed practices, namely a minimum weightloss goal of 1-2 lb per week and social networking; a strong discourse between evidence-informed weight-loss practices and the reported disparity in user experiences was highlighted. User expectations coincided with evidence-informed weight-loss practices and therefore did not provide any discourse.