Do Body Mass Index and Nutritional Risk Score 2002 Influence the In-Hospital Mortality of Patients Following Cardiac Arrest?

Abstract

Background: Contemporarily, cardiac arrest (CA) remains one of the leading causes of death. Poor nutritional status can increase the post-CA mortality risk. The aim of this study was to determine the relationship between body mass index (BMI) and Nutritional Risk Score 2002 (NRS 2002) results and in-hospital mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest. Methods: A retrospective study and analysis of medical records of 161 patients admitted to the ICU of the University Clinical Hospital in Wrocław (Wrocław, Poland) was conducted. Results: No significant differences in body mass index (BMI) and nutritional risk score (NRS 2002) values were observed between non-survivors and survivors. Non-survivors had significantly lower albumin concentration (p = 0.017) and total cholesterol (TC) (p = 0.015). In multivariate analysis BMI and NRS 2002 scores were not, per se, associated with the in-hospital mortality defined as the odds of death (Model 1: p: 0.700, 0.430; Model 2: p: 0.576, 0.599). Univariate analysis revealed significant associations between the hazard ratio (HR) and TG (p ≈ 0.017, HR: 0.23) and hsCRP (p ≈ 0.018, HR: 0.34). In multivariate analysis, mortality risk over time was influenced by higher scores in parameters such as BMI (HR = 0.164; p = 0.048) and hsCRP (HR = 1.006, p = 0.002). Conclusions: BMI and NRS 2002, on their own (unconditionally – in the whole study group) did not alter the odds of mortality in patients admitted to the intensive care unit (ICU) after in-hospital and out-of-hospital cardiac arrest. The risk of in-hospital mortality (expressed as hazard ratio – the risk over the time period of the study) increased with an increase in BMI but not with NRS 2002.

The Impact of Body Mass Index on In-Hospital Mortality in Post-Cardiac-Arrest Patients—Does Sex Matter?

“…While there have been several studies assessing the impact of BMI on prognosis in OHCA and IHCA survivors [15,19,20], very few of them have analysed sex differences in this regard. In our previous study (in which we did not disaggregate patients by gender), BMI results were not a factor which, on their own (unconditionally), altered the odds of mortality, but the risk of in-hospital mortality (expressed as hazard ratio-the risk over the study time period) increased with an increase in BMI in patients admitted to the intensive care unit (ICU) after IHCA and OHCA [21]. Considering the lack of sources from the literature and the results of our own research, we decided to investigate gender differences in this aspect.…”

Optimization of Nutrition after Brain Injury: Mechanistic and Therapeutic Considerations

“…Anoxic brain injury is a common sequela of cardiac arrest, contributing to 68% of out of hospital deaths, and is associated with poor neurological recovery in survivors [ 51 ]. Nutrition plays a significant role in post-cardiac arrest recovery, as malnutrition is associated with increased mortality [ 52 ]. The optimal nutritional approach to improve outcomes in this population is unknown.…”