Do brain mets grow while you wait? A volumetric natural history assessment of brain metastases from time of diagnosis to gamma knife treatment

Plunkett, Robert J.; Barone, Tara A.; Brady, William E.; Attwood, Kristopher; Prasad, Dheerendra

doi:10.1016/j.jocn.2019.07.019

Cited by 6 publications

(2 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…49,50 Recently one study documented that brain metastases can grow significantly rapidly; with 30% of tumors doubling in size between diagnosis and the first day of treatment. 51 Since treatment outcomes are dependent on tumor size, 52 it might be important to streamline patient management processes to minimize delays in treatment initiation. Concern also exists with regards to the possibility of having similar screened BCBM incidence to non-small cell lung cancer, for which screening is recommended.…”

Section: Discussionmentioning

confidence: 99%

<p>Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications</p>

Hadjipanteli

Doolan

Kyriacou

et al. 2020

CMAR

View full text Add to dashboard Cite

Breast cancer brain metastasis (BCBM) represents a major clinical challenge. Can MRI help in advancements in the management of BCBM? This review discusses MRI developments and the corresponding potential advancements in BCBM management. Methods: An exhaustive literature search was undertaken to identify studies which look into the potential of MRI in BCBM management. Seven hundred and eighty-four studies published from September 1984 to May 2020 were identified. Three topics are covered where MRI is not clinically established yet: 1) the prognosis of BCBM; 2) the screening of BC patients for BCBM development, and 3) the assessment of imaging features correlated to BC subtype. Results: Thirty-six studies were considered eligible for the purposes of this review. Ongoing progress is made with the identification of different BCBM characteristics and MRI metrics that might be related to prognosis. Progress has been made with the identification of different BCBM characteristics, including BCBM location, degree of edema, white matter disruption, tumor edge sharpness, and temporal muscle thickness. A more accurate prediction of prognosis could lead to more suitable patient management and treatment. The use of MRI in BCBM screening of the high-risk breast cancer population remains a controversial subject. To date, there are no results from clinical trials; however, there is a rising number of relatively small studies that show concern on this subject and support BCBM screening. It is important to oncologists to be able to assess the tumor subtype non-invasively. MRI features, which have shown some correlation with subtype, include the number of tumors, location, and their distribution in the brain. Advanced tools and metrics have been produced to carry out radiological characteristics analysis on MRI images. Assessing MRI features in more detail could provide a more personalized management of patients. Conclusion: Developments in the use of MRI have the potential to improve BCBM management.

show abstract

Section: Discussionmentioning

confidence: 99%

<p>Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications</p>

Hadjipanteli

Doolan

Kyriacou

et al. 2020

CMAR

View full text Add to dashboard Cite

show abstract

“…Хотелось бы отметить, что недавно одно исследование подтвердило, что метастазы в мозг могут довольно значимо быстро расти и при этом 30% метастатических опухолей увеличиваются вдвое в период между постановкой диагноза и первым днем начала специального лечения [39].…”

Section: Discussionunclassified

Magnetic resonance imaging in the diagnosis of breast cancer metastases in the brain (a brief review of the literature)

Паньшин

Нуднов

2022

Medicinskaâ vizualizaciâ

View full text Add to dashboard Cite

Breast cancer occupies the 1st place in the structure of oncological morbidity and mortality in the female population in the Russian Federation and is the second most common metastasis of primary solid malignant tumor after lung cancer, and the incidence of these often fatal lesions is currently increasing after improving systemic treatment.At the same time, the prognosis of patients who develop metastatic brain damage is usually unfavorable, since few of them live longer than 1 year.The purpose of the study: to analyze recent studies related to the use of magnetic resonance imaging in the diagnosis of breast cancer metastases in the brain.Conclusion. If there are characteristic results of MRI studies indicating the presence of possible primary gliomas of the brain, and not metastases, surgical intervention (biopsy) is necessary for histopathological studies, in order to finally establish the diagnosis of the underlying disease.

show abstract

Brain Metastases

Nieder,

Gaspar

2023

Target Volume Definition in Radiation Oncology

View full text Add to dashboard Cite

Do brain mets grow while you wait? A volumetric natural history assessment of brain metastases from time of diagnosis to gamma knife treatment

Cited by 6 publications

References 20 publications

<p>Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications</p>

<p>Breast Cancer Brain Metastasis: The Potential Role of MRI Beyond Current Clinical Applications</p>

Magnetic resonance imaging in the diagnosis of breast cancer metastases in the brain (a brief review of the literature)

Brain Metastases

Contact Info

Product

Resources

About