Do Carbon Nanotubes and Asbestos Fibers Exhibit Common Toxicity Mechanisms?

Gupta, Suchi Smita; Singh, Krishna Pal; Gupta, Satish; Dušinská, Maria; Rahman, Qamar

doi:10.3390/nano12101708

Cited by 26 publications

(15 citation statements)

References 185 publications

(193 reference statements)

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“…carbon nanotubes comes to light these days. Studies indicate that asbestos fibres and carbon nanotubes with certain dimensions exert toxic effects through similar mechanisms such as macrophage activation resulting in inflammation [103]. As mentioned above, carbon nanotubes are biopersistent, certain varieties being classified as possible human carcinogens [17].…”

Section: Discussionmentioning

confidence: 99%

Exaggerated Risk Perception of Low-Dose Exposures to Asbestos: Cui Bono?

Jargin¹

2022

J Surg

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Asbestos is a known carcinogen. Asbestos-related risks have been estimated on the basis of data from the past, when professional exposures were higher than today. Fibres are present in the environment due to erosion of surface deposits and human activities unrelated to asbestos industry. If searched for, asbestos fibres are often found post mortem. Bias can be encountered in asbestos research e.g. attributing of mesothelioma or lung cancer to asbestos if fibres are found, although cause-effect relationships remain unproven. Some studies rely on work or residence histories of questionable reliability. It can be reasonably assumed that the non-use of asbestos-containing brakes, fireproofing and insulation has increased the damage and numbers of victims of traffic accidents, fires and armed conflicts. Today, when a probability of conflicts seems to be enhanced, the attitude to asbestos should be changed. Asbestos is banned in some countries, while others continue production and exports. Some anti-asbestos activists have apparently served certain governments or companies. The same is partly true for the anti-nuclear activism. Different asbestos types have their technical advantages and preferred application areas. Reliable information about toxicity of fibres can be obtained in lifelong bioassays.

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Section: Discussionmentioning

confidence: 99%

Exaggerated Risk Perception of Low-Dose Exposures to Asbestos: Cui Bono?

Jargin¹

2022

J Surg

View full text Add to dashboard Cite

show abstract

“…carbon nanotubes comes to light these days. Studies indicate that asbestos fibers and carbon nanotubes with certain dimensions exert their toxic effects through the same mechanisms, in particular, chronic macrophage activation resulting in inflammation [148]. As mentioned above, carbon nanotubes are biopersistent and certain types of them have been classified as possible human carcinogens [22].…”

Section: Discussionmentioning

confidence: 99%

Asbestos-Related Diseases and Policies: an Update

Jargin¹

2022

Preprint

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Asbestos-related risks have been estimated on the basis of data from the past, when professional exposures were higher. Fibers are present in the environment due to erosion of surface deposits and human activities unrelated to asbestos industry. If searched for, asbestos fibers are frequently found at autopsies. Bias can be encountered in asbestos research e.g. attributing of mesothelioma and lung cancer to asbestos when fibers are present, although cause-effect relationships remain unproven. Some studies rely on work or residence histories of questionable reliability. Asbestos is banned in some countries while others are increasing production and exports. Asbestos is a low-cost material and an excellent reinforcing fiber. Different asbestos types have their technical advantages and preferred application areas. The traffic is safer with asbestos-containing brake linings. Asbestos cement constructions are sturdy and inexpensive. The fireproofing properties of asbestos are well known. It can be reasonably assumed that the non-use of asbestos-containing brakes, fireproofing and insulation lagging has increased the damage and numbers of victims of traffic accidents, fires and armed conflicts. Nowadays, when a probability of conflicts seems to be enhanced, the attitude to asbestos should be changed. Most importantly, asbestos-related science must be separated from economical and political interests. Reliable information can be obtained in lifelong bioassays.

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“…carbon nanotubes comes to light these days. Studies indicate that asbestos fibers and carbon nanotubes with certain dimensions exert their toxic effects through the same mechanisms, in particular, chronic macrophage activation resulting in inflammation (Gupta et al 2022). As mentioned above, carbon nanotubes are biopersistent and certain types of them have been classified as possible human carcinogens (Kane et al 2018).…”

Section: Discussionmentioning

confidence: 99%

Asbestos and anti-asbestos activism: medical and economical aspects

Jargin¹

2022

Preprint

View full text Add to dashboard Cite

Asbestos-related risks have been estimated on the basis of data from the past, when professional exposures were higher. Fibers are present in the environment due to erosion of surface deposits and human activities unrelated to asbestos industry. If searched for, asbestos fibers are frequently found at autopsies. Bias can be encountered in asbestos research e.g. attributing of mesothelioma and lung cancer to asbestos when fibers are found, although cause-effect relationships remain unproven. Some studies rely on work or residence histories of questionable reliability. Asbestos is a low-cost material and an excellent reinforcing fiber. Different asbestos types have their technical advantages and preferred application areas. The traffic is safer with asbestos-containing brake linings. Chrysotile cement constructions are sturdy and inexpensive. The fireproofing properties of asbestos are well known. It can be reasonably assumed that the non-use of asbestos-containing brakes, fireproofing and insulation lagging has increased the damage and numbers of victims of traffic accidents, fires and armed conflicts. Nowadays, when a probability of conflicts seems to be enhanced, the attitude to asbestos should be changed. Most importantly, asbestos-related science must be separated from economical and political interests. Reliable information can be obtained in lifelong bioassays.

show abstract

Do Carbon Nanotubes and Asbestos Fibers Exhibit Common Toxicity Mechanisms?

Cited by 26 publications

References 185 publications

Exaggerated Risk Perception of Low-Dose Exposures to Asbestos: Cui Bono?

Exaggerated Risk Perception of Low-Dose Exposures to Asbestos: Cui Bono?

Asbestos-Related Diseases and Policies: an Update

Asbestos and anti-asbestos activism: medical and economical aspects

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