Do Clinical Characteristics Predict the Presence of Small Bowel Angioectasias on Capsule Endoscopy?

DeBenedet, Anthony T.; Saini, Sameer D.; Takami, Mimi; Fisher, Laurel

doi:10.1007/s10620-010-1506-9

Cited by 37 publications

(24 citation statements)

References 32 publications

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“…In our study, we observed that age was significantly associated with higher prevalence of SB angioectasias, which is in line with the results of other previous studies, endorsing the possibility of a degenerative process behind the pathogenesis of GI angioectasias [13, 15, 22]. No significant differences were observed between the two groups regarding gender.…”

Section: Discussionsupporting

confidence: 92%

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Is It Possible to Predict the Presence of Intestinal Angioectasias?

Gonçalves

Magalhães

Carvalho

et al. 2014

Diagnostic and Therapeutic Endoscopy

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Background and Aim. Angioectasias are the most common vascular anomalies found in the gastrointestinal tract. In small bowel (SB), they can cause obscure gastrointestinal bleeding (OGIB) and in this setting, small bowel capsule endoscopy (SBCE) is an important diagnostic tool. This study aimed to identify predictive factors for the presence of SB angioectasias, detected by SBCE. Methods. We retrospectively analyzed the results of 284 consecutive SBCE procedures between April 2006 and December 2012, whose indication was OGIB, of which 47 cases with SB angioectasias and 53 controls without vascular lesions were selected to enter the study. Demographic and clinical data were collected. Results. The mean age of subjects with angioectasias (70.9 ± 14.7) was significantly higher than in controls (53.1 ± 18.6; P < 0.001). The presence of SB angioectasias was significantly higher when the indication for the exam was overt OGIB versus occult OGIB (13/19 versus 34/81, P = 0.044). Hypertension and hypercholesterolemia were significantly associated with the presence of SB angioectasias (38/62 versus 9/38, P < 0.001 and 28/47 versus 19/53, P = 0.027, resp.). Other studied factors were not associated with small bowel angioectasias. Conclusions. In patients with OGIB, overt bleeding, older age, hypercholesterolemia, and hypertension are predictive of the presence of SB angioectasias detected by SBCE, which may be used to increase the diagnostic yield of the SBCE procedure and to reduce the proportion of nondiagnostic examinations.

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Section: Discussionsupporting

confidence: 92%

“…Overall, angioectasias are the most common origin of OGIB, being responsible for approximately 30–40% of the cases [3, 13, 14]. Angioectasias consist of dilated, ectatic, tortuous, thin-walled vessels of the mucosa or submucosa, without inflammation or fibrosis [13, 15]. …”

Section: Introductionmentioning

confidence: 99%

Is It Possible to Predict the Presence of Intestinal Angioectasias?

Gonçalves

Magalhães

Carvalho

et al. 2014

Diagnostic and Therapeutic Endoscopy

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“…3548-50 The research studies that EMERSE has supported span many topic areas in health sciences. 355152 Several papers explicitly acknowledged the enabling role that EMERSE played in the studies which allowed the investigators to “systematically identify data within the electronic medical record,” 33 and helped to accomplish “a standardized, accurate, and reproducible electronic medical record review.” 3637 Table 1 exhibits 14 peer-reviewed publications appearing in 2014 alone that were supported by the use of EMERSE. A full list of the publications supported by EMERSE to date, of which we are aware, is provided in Appendix B.…”

Section: Resultsmentioning

confidence: 99%

“…As part of the results validation process several studies explicitly examined the efficacy of EMERSE and concluded that the system was instrumental in ensuring the quality of chart review while significantly reducing manual efforts. 333637 To the best of our knowledge, this is the first comprehensive description of an EHR search tool that has been used in a production setting by many real end users for multiple years and for a wide variety of clinical, operational, and research tasks. We believe our experience of designing, building, maintaining, and disseminating EMERSE will provide useful insights to the researchers who have a similar need for an HER search engine and will help potential users of such an EHR search engine to understand what types of problems that such tools can help solve.…”

Section: Background and Significancementioning

confidence: 99%

Supporting information retrieval from electronic health records: A report of University of Michigan’s nine-year experience in developing and using the Electronic Medical Record Search Engine (EMERSE)

Hanauer

Mei

Law

et al. 2015

Journal of Biomedical Informatics

360

225

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Objective This paper describes the University of Michigan's nine-year experience in developing and using a full-text search engine designed to facilitate information retrieval (IR) from narrative documents stored in electronic health records (EHRs). The system, called the Electronic Medical Record Search Engine (EMERSE), functions similar to Google but is equipped with special functionalities for handling challenges unique to retrieving information from medical text. Materials and Methods Key features that distinguish EMERSE from general-purpose search engines are discussed, with an emphasis on functions crucial to (1) improving medical IR performance and (2) assuring search quality and results consistency regardless of users' medical background, stage of training, or level of technical expertise. Results Since its initial deployment, EMERSE has been enthusiastically embraced by clinicians, administrators, and clinical and translational researchers. To date, the system has been used in supporting more than 750 research projects yielding 80 peer-reviewed publications. In several evaluation studies, EMERSE demonstrated very high levels of sensitivity and specificity in addition to greatly improved chart review efficiency. Discussion Increased availability of electronic data in healthcare does not automatically warrant increased availability of information. The success of EMERSE at our institution illustrates that free-text EHR search engines can be a valuable tool to help practitioners and researchers retrieve information from EHRs more effectively and efficiently, enabling critical tasks such as patient case synthesis and research data abstraction. Conclusion EMERSE, available free of charge for academic use, represents a state-of-the-art medical IR tool with proven effectiveness and user acceptance.

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“…Th e introduction into the US of capsule endoscopy in 2000 and deep enteroscopy in 2004 further advanced the ability to visualize and treat small-bowel GIADs compared with traditional small-bowel series and push enteroscopy. Th e presence of GIADs in the upper GI tract has been shown to be a predictor of jejunal small-bowel GIADs on subsequent capsule endoscopy examinations ( 11 ).…”

Section: Introductionmentioning

confidence: 99%

Management of Gastrointestinal Angiodysplastic Lesions (GIADs): A Systematic Review and Meta-Analysis

Jackson¹,

Gerson

2014

American Journal of Gastroenterology

154

113

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Do Clinical Characteristics Predict the Presence of Small Bowel Angioectasias on Capsule Endoscopy?

Abstract: Patients with AVMs on EGD have an increased risk of jejunal AVMs on CE, particularly if they are elderly. Future studies should validate these findings in a prospective cohort.

Cited by 37 publications

References 32 publications

Is It Possible to Predict the Presence of Intestinal Angioectasias?

Is It Possible to Predict the Presence of Intestinal Angioectasias?

Supporting information retrieval from electronic health records: A report of University of Michigan’s nine-year experience in developing and using the Electronic Medical Record Search Engine (EMERSE)

Management of Gastrointestinal Angiodysplastic Lesions (GIADs): A Systematic Review and Meta-Analysis

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