Do Demographics and Comorbidities Act as Predictors of Co-diagnosis of Attention-deficit/Hyperactivity Disorder in Autism Spectrum Disorder?

Ashraf, Sahar; Eskander, Noha; Amuk, Ozge Ceren; Patel, Rikinkumar S

doi:10.7759/cureus.7798

Cited by 1 publication

(1 citation statement)

References 11 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Sleep disturbances co-occur with psychiatric disorders including attention-deficit hyperactivity disorder (ADHD), autism spectrum disease (ASD), anxiety disorders, and major depressive disorder (MDD) [2]. As per a recent nationwide study, boys with ASD have two times higher likelihood of comorbid ADHD, with prevalence in white adolescents [3].…”

Section: Introductionmentioning

confidence: 99%

Perspective on Melatonin Use for Sleep Problems in Autism and Attention-Deficit Hyperactivity Disorder: A Systematic Review of Randomized Clinical Trials

Parvataneni¹,

Srinivas²,

Shah³

et al. 2020

Cureus

Self Cite

View full text Add to dashboard Cite

Melatonin is a hormone produced by the pineal gland and is available over the counter for treating sleep problems in the pediatric population. We conducted a systematic review of randomized clinical trials (RCTs) on MEDLINE and included six studies that met our inclusion criteria. RCTs were conducted in patients from two to 18 years of age with a diagnostic and statistical manual of mental disorders (DSM)-IV diagnosis of autism spectrum disease (ASD) and/or attention-deficit hyperactivity disorder (ADHD) in both short-term and long-term RCTs ranging from eight-week to 52-week studies. The mean difference in the children's sleep disorder showed statistically significant improvement in sleep duration and sleep latency onset compared to the placebo. Overall, a high response rate was observed in the melatonin group compared to the placebo in treating sleep problems in children. Melatonin is a well-tolerated and safe medication in the dose range of 2-10 mg/day in the child and adolescent population.

show abstract

Section: Introductionmentioning

confidence: 99%