Do Fats or Carbohydrates Shorten Our Lives? What Does the Pure Study Reveal?

Демкина, А. Е.; Бойцов, С. А.

doi:10.15829/1560-4071-2018-6-202-206

Cited by 3 publications

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References 12 publications

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“…При этом нет жестких клинических рекомендаций по рациональному питанию, чаще рассматривают преимущества и недостатки отдельных видов диет. Но отмечено негативное влияние легкоусвояемых углеводов в модуляции постпрандиальной гликемии [8,9,27].…”

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Treatment of metabolic syndrome in young patients with vitamin D deficiency

Alekseeva

2020

Terapevticheskii arkhiv

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Aim.The purpose of the study is to increase the effectiveness of treatment of metabolic syndrome (MS) in young patients with vitamin D deficiency. Materials and methods.The study involved 54 patients with MS and vitamin D deficiency (50% of women, 50% of men), aged 2044years. To assess the concentration of melatonin at a young age, a control group of 42 practically healthy volunteers with comparable demographic characteristics with no signs of MS was formed. Results.In patients with MS and vitamin D deficiency, there was a significant decrease in the average daily level of 6-sulfatoxymelatonin in the urine by 3.7 times, compared with the group of individuals without MS. Patients with MS and vitamin D deficiency (n=54) were randomly assigned to two groups with comparable clinical and demographic characteristics. Patients of the 1st group (n=27) observed dietary recommendations and took the drug Metformin at a dose of 1700 mg/day for 12 months. In the 2nd group (n=27), in addition to the one indicated in the 1st treatment group, correction of vitamin D deficiency was performed (a micelled preparation of cholecalciferol at a dose of 4000 IU/day, for 6 months, then 2000 IU/day for another 6 months) and the level of melatonin (melatonin preparation at a dose of 3 mg/day for 6 months). After treatment in young patients with MS, there was a significant change in the median of the studied parameters in all therapeutic groups, but more pronounced dynamics was observed in group 2 in terms of: WC in women, BMI, insulin resistance index, LDL cholesterol, TG, hs-CRP, hs-TNF-, IL-6, leptin. Conclusion.To increase the effectiveness of MS treatment in young patients with vitamin D deficiency, it is necessary to determine the level of melatonin (urinary 6-sulfatoxymelatonin) and, if it decreases, carry out correction of melatonin and 25 (OH) vitamin D in addition to the standard therapy of this syndrome.

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Treatment of metabolic syndrome in young patients with vitamin D deficiency

Alekseeva

2020

Terapevticheskii arkhiv

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Prevalence of metabolic syndrome components in men of an open urban population according to different assessment criteria

Акимова¹,

Akimov²,

Petelina³

2021

Profil. med.

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Metabolic Syndrome in Women of an Open Urban Population According to Different Assessment Criteria

Akimova,

Bessonova,

Akimov

2024

Vrach

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Objective. To study the prevalence of metabolic syndrome (MS) and its components among women in an open urban population according to two assessment criteria. Materials and methods. A cross-sectional epidemiological study was conducted on a representative sample of an open urban population aged 25–64 years in Tyumen. The sample consisted of 1000 females, included four decades of life in equal shares, the response rate was 70.3%. To analyze the prevalence of MS and its components, the NCEP ATP III and IDF assessment criteria were used. Results. Among women 25–64 years old in an open urban population, according to the IDF criteria, a high prevalence of abdominal obesity (AO), hyperglycemia, and hypocholesterolemia of high-density lipoproteins (hypo-HDL cholesterolemia) was established; according to various evaluation criteria, the average prevalence of arterial hypertension (AH) and hyperthyroidism was established. According to the IDF criteria, a consistent age trend was determined in the prevalence of hypertension and AO across the entire age range. According to various assessment criteria, the prevalence of hyperglycemia formed an age trend from the fourth to the sixth decades of life, hyperthyroidism – only in older age categories, the prevalence of hypo-HDL cholesterolemia showed its absence in the entire age range. In an open female population aged 25–64 years in Tyumen, a high prevalence of MS was established according to two classifications (NCEP ATP – 24.3%, IDF – 27.3%). In the structure of the MS according to the NCEP ATP and IDF criteria, the combination of AH, AO and hyperglycemia predominates (12.6% and 15.5%). Conclusion. For effective planning of evidence-based preventive programs in the region among women of working age, it is necessary to study the associative relationships of the MS and its components, taking into account behavioral and psychosocial characteristics, as well as the risks of developing cardiovascular and endocrinological pathologies in the studied population.

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Do Fats or Carbohydrates Shorten Our Lives? What Does the Pure Study Reveal?

Cited by 3 publications

References 12 publications

Treatment of metabolic syndrome in young patients with vitamin D deficiency

Treatment of metabolic syndrome in young patients with vitamin D deficiency

Prevalence of metabolic syndrome components in men of an open urban population according to different assessment criteria

Metabolic Syndrome in Women of an Open Urban Population According to Different Assessment Criteria

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