Emergency medicine is often a specialty defined by diagnostic uncertainty when worried patients present with constellations of symptoms seeking explanation and relief. Abdominal pain is a common chief complaint among adult emergency department (ED) patients, with recurrent symptoms in the subsequent days, weeks, months, and even years, sometimes prompting repeat evaluations. 1 The differential diagnosis is broad and diverse, including multiple organs and systems and extraabdominal causes. Ideally, clinical practice guidelines (CPGs) synthesize the entirety of evidence for questions relevant to an explicitly defined patient population and outcomes, but until now no CPG existed for the scenario of recurrent abdominal pain. Consequently, significant practice variation exists in the diagnostic and therapeutic approach to this clinical condition. 2The Society for Academic Emergency Medicine (SAEM) second "Guidelines for Reasonable and Appropriate Care in the Emergency Department 2 (GRACE-2)" article provides that CPG with adherence to Grading of Recommendations, Assessment, Development and Evaluations (GRADE) methodology including incorporation of patient priorities and external stakeholders. 3 Through adherence