Do intra-articular corticosteroid injections help delay knee replacement surgery in patients with knee osteoarthritis?

Abstract

The evidence is conflicting. Corticosteroid injections (CSI) are not associated with a reduced risk total knee arthroplasty (TKA) in patients with knee osteoarthritis (strength of recommendation [SOR]: B, meta-analysis of 2 cohort studies). But CSI may increase time to TKA, although the clinical significance of this delay is unknown (SOR: B, based on 2 cohort studies).