The patent application process produces asymmetric information between insider to the firms applying for a patent and other market participant. We investigate whether insiders trade upon such private information that emerges during to patent application process. Our results show that insiders in R&D intensive industries trade on this private information before the patent grant is publicly disclosed. We also investigate insider trading after the official patent grant date, that is, after information asymmetry between insiders and outsiders is presumably dissolved. In case the stock market reacts favorably to the patent disclosure we expect and find insiders to sell shares subsequent to the grant in order to cash in on their equity holdings at a higher share price. Jelcodes:O31,G00