Do Nutritional Factors Interact with Chronic Musculoskeletal Pain? A Systematic Review

Abstract

Dietary patterns may play an important role in musculoskeletal well-being. However, the link between dietary patterns, the components of patients’ diet, and chronic musculoskeletal pain remains unclear. Therefore, the purpose of this review was to systematically review the literature on the link between dietary patterns, the components of patients’ diet and chronic musculoskeletal pain. This review was conducted following the “Preferred Reporting Items for Systematic reviews and Meta-Analyses” (PRISMA) guidelines and was registered in PROSPERO with the registration number CRD42018110782. PubMed, Web of Science, and Embase online databases were searched. After screening titles and abstracts of 20,316 articles and full texts of 347 articles, 12 eligible articles were included in this review, consisting of nine experimental and three observational studies. Seven out of nine experimental studies reported a pain-relieving effect of dietary changes. Additionally, protein, fat, and sugar intake were found to be associated with pain intensity and pain threshold. In conclusion, plant-based diets might have pain relieving effects on chronic musculoskeletal pain. Patients with chronic rheumatoid arthritis pain can show inadequate intake of calcium, folate, zinc, magnesium, and vitamin B6, whilst patients with fibromyalgia can show a lower intake of carbohydrates, proteins, lipids, vitamin A-E-K, folate, selenium, and zinc. Chronic pain severity also shows a positive relation with fat and sugar intake in osteoarthritis, and pain threshold shows a positive association with protein intake in fibromyalgia.

Valores De LDL-C E Consumo Habitual De Ácido Graxo Saturado Esteárico Em Adultos Do Município De João Pessoa/Pb: Um Olhar Para Hipercolesterolemia

“…O consumo de carboidratos acima das Recommended Dietary Allowances (RDA) (130g/ dia) (IOM, 2006) é fator agravante para o aumento de peso corporal e consequentemente de reservas adiposas, o que foi evidenciado através da avaliação antropométrica, com elevação de IMC e percentual de gordura corporal dos indivíduos avaliados. Também, o consumo excessivo de açúcares e gorduras é apontado em diversos estudos como associado à severidade da dor (RONDANELLI et al, 2018;DRAGAN et al, 2020;ELMA et al, 2020).…”

“…Apesar da escassez de estudos que avaliam a melhora da dor como desfecho primário para alterações na alimentação, há alguns estudos que avaliam o impacto da alimentação da modulação da dor crônica (BRAIN et al, 2018). Uma revisão sistemática e metanálise realizada por Elma et al (2020) sobre o impacto de padrões alimentares em dores musculoesqueléticas crônicas apontou ingestão excessiva de açúcares e gorduras como associada à intensidade da dor e a alimentação baseada em plantas como possivelmente relacionada à melhora da dor. Esta, assim como a dieta mediterrânea, são discutidas por serem ricas em compostos bioativos e desempenharem papel anti-inflamatório no indivíduo (RONDANELLI et al, 2018;DRAGAN et al, 2020).…”

Serum soluble urokinase plasminogen activator receptor in adolescents: interaction of chronic pain and obesity

“…As an example of its potential to assess treatment response, it has been suggested that obesity-driven inflammation in those with chronic pain may respond to nutritional interventions. 15 , 16 …”

Dietary Patterns and Interventions to Alleviate Chronic Pain

“…Besides inflammation, low dietary intake of micronutrients, especially omega-3 fatty acids, vitamins B1, B3, B6, B12 and D, magnesium, zinc and β-carotene, is also associated with chronic neuropathic or inflammatory pain [13]. Supplementation of diet with these specific nutrients contributes to alleviation of CP [29], as observed in systematic reviews on chronic pelvic pain [22], low back pain [30], rheumatoid arthritis or joint pain secondary to inflammatory bowel disease [31,32], migraine [33], chronic noncancer pain [34,35], pain in chronic liver disease [36], or aromatase inhibitor-related arthralgia in breast cancer [37].…”