Do Secondary Progressive Multiple Sclerosis patients benefit from Computer- based cognitive neurorehabilitation? A randomized sham controlled trial

Messinis, Lambros; Kosmidis, Mary H.; Nasios, Grigorios; Konitsiotis, Spyridon; Ntoskou, Aikaterini; Bakirtzis, Christos; Grigoriadis, Nikolaos; Patrikelis, Panayiotis; Panagiotopoulos, Elias; Gourzis, Philippos; Malefaki, Sonia; Papathanasopoulos, Panagiotis

doi:10.1016/j.msard.2020.101932

Cited by 33 publications

(50 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…What is feasible? Diagnose MS sooner, detect CI earlier and include it in clinical decisions, start treatment early and constantly follow through with more effective DMTs, find medications for CNS tissue repair, adopt strategies for "reserve and brain maintenance" (93), and, of course, do more research on neurorehabilitation and neuromodulation since they seem to be at least in part effective, even in advanced disease stages (94), and may enhance the brain's plasticity and alter disease course. This is all with the ultimate goal of implementing these methods in routine MS management.…”

Section: Discussionmentioning

confidence: 99%

Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation

2020

Self Cite

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation

2020

Self Cite

View full text Add to dashboard Cite

“…Messinis and colleagues recently conducted a randomized controlled trial on the impact of the computer-based cognitive neurorehabilitation for the secondary progressive multiple sclerosis (SPMS) patients [ 11 ]. They have reported that training by RehaCom™ software was effective for the rehabilitation of the SPMS through reduction of the cognitive fatigue, improvement of cognition, and quality of life in the considered patients [ 11 ]. Similarly, neuroplasticity is also considered as a part of the neurorehabilitation program for multiple sclerosis patients [ 12 ].…”

Section: Major Types Of Health Conditions Require Rehabilitationsmentioning

confidence: 99%

Novel Human-Centered Robotics: Towards an Automated Process for Neurorehabilitation

Parre

Sujatha

2021

Neurology Research International

View full text Add to dashboard Cite

The global requirement of patient rehabilitation has surged with time due to the growing number of accidents, injuries, age-related issues, and other aspects. Parallelly, the cost of treatment and patient care also increased in a manifold. Moreover, constant monitoring and support for the patients having physical disabilities have become an ongoing challenge to the medical system. Robotics-based neurorehabilitation has reduced the human error while assisting such patients, precisely interpreting the signals, and communicating to the patient. Gradual precise application and improvement of the technology with time yielded a novel direction for patient care and support. The interdisciplinary contribution of many advanced technical branches allowed us to develop robotics-based assistance with high precision for the upper limb and the lower limb impairments. The present review summarizes the generation and background of robotic implementation for patient support, progress, present status, and future requirements.

show abstract

“…Amongst the included RCTs, 20 were included in the meta-analysis assessing the efficacy of mHeath for rehabilitation [24,[26][27][28][29][30][31][33][34][35][36][37]39,40,44,45,[47][48][49]51,65], representing 1,393 pwMS. When considering all the studies and ICF domains together, the heterogeneity between the studies was moderate (tau 2 = 0.30, 95%CI [0.26; 0.62]), therefore we decided to use random-effect model.…”

Section: Rehabilitationmentioning

confidence: 99%

“…BrainHQ [27,32,39,41,42] Lumosity [26] RehaCom [24,30,33] BrainStim [28] COGNI-TRAcK [31] MAPPS-MS* [35] APT [25] MS-HAT [43] Walk-With-Me [50] AKL-T03 [51] MSdialog [55] Floodlight [57] Fatigue RehaCom [24,33] ELEVEDIA [37] MAPPS-MS [35] SitLess & MoveMore [46] Walk-With-Me [50] AKL-T03 [51] MSdialog [55] MS TeleCoach [56] FatigueApp.com [58] Quality of Life ELEVEDIA [37] MBSR [38] MS-HAT [43] webbasedphysio.com [47] RehaCom [48] RELAXaHEAD [49] Walk-With-Me [50] MCCO-enhanced [54] ElevateMS [59] Activity Level MS-HAT system [34] SitLess & MoveMore [46] Walk-With-Me [50] Floodlight [57] ElevateMS [59] Motor Function MS-HAT system [34,43] webbasedphysio.com [47] / * The cognitive training module of MAPPS-MS is done with Luminosity.…”

Section: Cognitionmentioning

confidence: 99%

Are mHealth a Useful Tool for Self-Assessment and Rehabilitation of People With Multiple Sclerosis? A Review

Bonnechère¹,

Rintala²,

Spooren³

et al. 2021

Preprint

View full text Add to dashboard Cite

The development of mobile technology and internet mobile offers new possibilities in both rehabilitation and for patients’ assessment in a longitudinal and MS management perspective. However, because the mobile health applications (mHealth) have only been developed recently, the level of evidence supporting the use of mHealth in patients with multiple sclerosis (pwMS) is currently unclear. Therefore, this study aims to list and describe the different mHealth available for rehabilitation and self-assessment of pwMS and to define the level of evidence supporting these interventions for functioning problems categorized within the International Classification of Functioning, Disability and Health (ICF). 36 studies, performed with 22 different mHealth, were included in this review, 30 about rehabilitation and 6 for self-assessment, representing 3,091 patients. For rehabilitation, most of the studies were focusing on cognitive function and fatigue. Concerning the efficacy we found a small but significant effect of the use of mHealth for cognitive training (SMD = 0.28 [0.12 ; 0.45]) and moderate effect for fatigue (SMD = 0.61 [0.47 ; 0.76]). mHealth is a promising tool in pwMS but more studies are needed to validate these solutions in the others ICF categories. More replications studies are also needed as most of the mHealth have only been assessed in one single study.

show abstract

Do Secondary Progressive Multiple Sclerosis patients benefit from Computer- based cognitive neurorehabilitation? A randomized sham controlled trial

Cited by 33 publications

References 49 publications

Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation

Cognitive Impairment and Brain Reorganization in MS: Underlying Mechanisms and the Role of Neurorehabilitation

Novel Human-Centered Robotics: Towards an Automated Process for Neurorehabilitation

Are mHealth a Useful Tool for Self-Assessment and Rehabilitation of People With Multiple Sclerosis? A Review

Contact Info

Product

Resources

About