Do Temporal Eating Patterns Differ in Healthy versus Unhealthy Overweight/Obese Individuals?

Mazri, Fatin Hanani; Manaf, Zahara Abdul; Shahar, Suzana; Ludin, Arimi Fitri Mat; Karim, Norwahidah Abdul; Hazwari, Nur Diyana Dalila; Kek, Qi Wen; Basir, Siti Munirah Abdul; Arifin, Asnida

doi:10.3390/nu13114121

Cited by 11 publications

(10 citation statements)

References 59 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Another strategy would be to utilize chronic taVNS to suppress food cravings and prevent snacking throughout the day. Preventing snacking in the late evening may be particularly effective for weight loss, because chrono‐nutritional studies have demonstrated that consuming high caloric meals later in the day is associated with obesity (Mazri et al, 2021 ; Okada et al, 2019 ). Even though our findings are encouraging, more research including chronic application of taVNS is needed to address issues such as the optimal stimulation parameters or the timing of stimulation relative to food intake, before chronic taVNS can be developed into a clinical tool to assist obese patients with achieving their weight loss goals.…”

Section: Discussionmentioning

confidence: 99%

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

Kozorosky¹,

Lee²,

Lee³

et al. 2022

Physiological Reports

View full text Add to dashboard Cite

Vagus nerve stimulation (VNS) facilitates weight loss in animals and patients treated with VNS for depression or epilepsy. Likewise, chronic transcutaneous auricular VNS (taVNS) reduces weight gain and improves glucose tolerance in Zucker diabetic fatty rats. If these metabolic effects of taVNS observed in rats translate to humans is unknown. Therefore, the hypothesis of this study was that acute application of taVNS affects glucotropic and orexigenic hormones which could potentially facilitate weight loss and improve glucose tolerance if taVNS were applied chronically. In two single‐blinded randomized cross‐over protocols, blood glucose levels, plasma concentrations of insulin, C‐peptide, glucagon, leptin, and ghrelin, together with heart rate variability and baroreceptor‐heart rate reflex sensitivity were determined before and after taVNS (left ear, 10 Hz, 300 µs, 2.0–2.5 mA, 30 min) or sham‐taVNS (electrode attached to ear with the stimulator turned off). In a first protocol, subjects ( n = 16) were fasted throughout the protocol and in a second protocol, subjects ( n = 10) received a high‐calorie beverage (220 kCal) after the first blood sample, just before initiation of taVNS or sham‐taVNS. No significant effects of taVNS on heart rate variability and baroreceptor‐heart rate reflex sensitivity and only minor effects on glucotropic hormones were observed. However, in the second protocol taVNS significantly lowered postprandial plasma ghrelin levels (taVNS: −115.5 ± 28.3 pg/ml vs. sham‐taVNS: −51.2 ± 30.6 pg/ml, p < 0.05). This finding provides a rationale for follow‐up studies testing the hypothesis that chronic application of taVNS may reduce food intake through inhibition of ghrelin and, therefore, may indirectly improve glucose tolerance through weight loss.

show abstract

Section: Discussionmentioning

confidence: 99%

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

Kozorosky¹,

Lee²,

Lee³

et al. 2022

Physiological Reports

View full text Add to dashboard Cite

show abstract

“…Greater energy intake towards earlier part of the day and smaller intake towards later part of the day is beneficial for both chronotypes [48].…”

Section: Temporal Pattern Of Energy Intakementioning

confidence: 98%

“…In addition, the majority of morning chronotypes did not achieve the 75% energy intake recommendation in the early window. Our recent work shows that the energy intake of 62-64% during the early window has benefits for metabolic health among overweight/obese adults [48]. Therefore, the recommendation was revised to improve compliance and at the same time achieve a significant level of intake towards clinical benefits.…”

Section: Refinement Of the Integrated Chrono-nutrition Weight Reducti...mentioning

confidence: 99%

Development and Evaluation of Integrated Chrono-Nutrition Weight Reduction Program among Overweight/Obese with Morning and Evening Chronotypes

Mazri

Manaf

Shahar

et al. 2022

IJERPH

Self Cite

View full text Add to dashboard Cite

This paper describes the development of an integrated chrono-nutrition weight reduction program and the evaluation of the attendance, retention, satisfaction and compliance towards the chrono-nutrition components among morning and evening chronotypes for overweight/obese non-shift workers. The present study was conducted in two phases: Phase I was composed of needs assessments on the chronotypes’ dietary patterns and chrono-nutrition through a scoping review and integrating the chrono-nutrition components (temporal eating pattern, meal timing and sleeping habits) alongside the existing weight reduction module, SLIMSHAPE™. Phase II consisted of a feasibility study to evaluate the integrated chrono-nutrition weight reduction program (SLIMSHAPE™ Chrono). A total of 91 overweight/obese non-shift workers participated in the 12-week weight reduction program (Age: 39.6 ± 6.3 years; 74.7% women; BMI: 31.2 ± 4.5 kg/m2). Low attrition rate was recorded, with 85 participants (93.4%) completing the pre- and post-intervention assessments. Overall, morning and evening chronotypes had increased their % energy intake in the early eating window (MT: 64.8 vs. 67.2%, ET: 62.7 vs. 65.6%, Mean difference (MD): 2.8, 95%CI: 0.3, 5.1, p = 0.028) and reduced their intake in the late eating window (MT: 35.2 vs. 32.8%, ET: 37.3 vs. 34.4%, MD: −2.8, 95%CI: −5.1, −0.3, p = 0.028) and earlier midpoint of eating (MT: 14:02 vs. 13:49; ET: 14:27 vs. 14:18, 95%CI: −0.4, −0.02, p = 0.029) and had a reduced night eating syndrome score (MT: 10.0 vs. 8.9; ET: 10.7 vs. 8.9, MD: −1.5, 95%CI: −2.5, −0.5, p = 0.004). There was no significant change in the first (MT: 08:12 vs. 08:04, ET: 08:24 vs. 08:22, MD: −0.1, 95%CI: −0.2, 0.03, p = 0.170) and last mealtime (MT: 19:52 vs. 19:33, ET: 20:29 vs. 20:14, MD: −0.3, 95%CI: −0.6, −0.04, p = 0.081), eating duration (MT: 11.7 vs. 11.5 h, ET: 12.1 vs. 11.9 h, MD: −0.2, 95%CI: −0.6, 0.2, p = 0.251) and the elapse time between sleep onset and last meal (MT: 3.1 vs. 3.5 h, ET: 3.5 vs. 3.2 h, MD: 0.1, 95%CI: −0.3, 0.4, p = 0.678). In terms of sleep, evening chronotypes increased their sleep duration (MD: 0.8 h, 95% CI: 0.4, 1.2, p < 0.001) and reduced social jetlag (MD: 19 min, 95% CI: 1.7, 36.3, p = 0.031) post-intervention compared to morning chronotypes. The integrated chrono-nutrition weight reduction program among morning and evening chronotypes improved the temporal pattern of energy intake, meal timing, night eating syndrome and sleep habits post-intervention. The chrono-nutrition practice could be a potentially modifiable behavior as an adjunct strategy in weight management.

show abstract

“…Observational data have revealed that meal regularity and, in particular, high energy intake in the morning is associated with wellbeing outcomes ( 216 ). It is important to note that food timing also influences the metabolic state of obese subjects: as observed by Mazri et al., early temporal patterns of energy and macronutrient intake characterized obesity with healthy metabolic status ( 217 ). In diabetic patients, morning distribution of food intake, especially a carbohydrate-rich breakfast, accelerates weight loss, reduces appetite and craving, and thus improves metabolic parameters, such as postprandial glycemia and glycated hemoglobin ( 218 – 220 ).…”

Section: Nutrition As Metronome: Circadian Re-synchronizationmentioning

confidence: 99%

Chrono-communication and cardiometabolic health: The intrinsic relationship and therapeutic nutritional promises

Senesi

Ferrulli²,

Luzi³

et al. 2022

Front. Endocrinol.

View full text Add to dashboard Cite

Circadian rhythm, an innate 24-h biological clock, regulates several mammalian physiological activities anticipating daily environmental variations and optimizing available energetic resources. The circadian machinery is a complex neuronal and endocrinological network primarily organized into a central clock, suprachiasmatic nucleus (SCN), and peripheral clocks. Several small molecules generate daily circadian fluctuations ensuring inter-organ communication and coordination between external stimuli, i.e., light, food, and exercise, and body metabolism. As an orchestra, this complex network can be out of tone. Circadian disruption is often associated with obesity development and, above all, with diabetes and cardiovascular disease onset. Moreover, accumulating data highlight a bidirectional relationship between circadian misalignment and cardiometabolic disease severity. Food intake abnormalities, especially timing and composition of meal, are crucial cause of circadian disruption, but evidence from preclinical and clinical studies has shown that food could represent a unique therapeutic approach to promote circadian resynchronization. In this review, we briefly summarize the structure of circadian system and discuss the role playing by different molecules [from leptin to ghrelin, incretins, fibroblast growth factor 21 (FGF-21), growth differentiation factor 15 (GDF15)] to guarantee circadian homeostasis. Based on the recent data, we discuss the innovative nutritional interventions aimed at circadian re-synchronization and, consequently, improvement of cardiometabolic health.

show abstract

Do Temporal Eating Patterns Differ in Healthy versus Unhealthy Overweight/Obese Individuals?

Cited by 11 publications

References 59 publications

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

Transcutaneous auricular vagus nerve stimulation augments postprandial inhibition of ghrelin

Development and Evaluation of Integrated Chrono-Nutrition Weight Reduction Program among Overweight/Obese with Morning and Evening Chronotypes

Chrono-communication and cardiometabolic health: The intrinsic relationship and therapeutic nutritional promises

Contact Info

Product

Resources

About