Do they know what is sepsis time? Septic Patients Survey Enrolling Staffs study

Assunção, Murillo Santucci César de; Machado, FR; Akamine, Nelson; Cardoso, Guttemberg S.; Mello, Patrícia Machado Veiga de Carvalho; Telles, J; Nunes, André Luis B.; Oliveira, Mariana Aparecida Nobre; Réa-Neto, Álvaro; Clleva, R; Dias, F. R. T.

doi:10.1186/cc5205

Cited by 4 publications

(1 citation statement)

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“…The authors found that as few as 27.3% of physicians were able to identify a case of sepsis, while 56.7% could identify a severe sepsis case. 18 The heterogeneous presentation of a septic patient can render the disease difficult to diagnose, especially for non-intensivists and in patients on inpatient wards. Recognition of sepsis is a key issue and should be a target in educational campaigns.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Duration of Organ Dysfunction on the Outcome of Patients with Severe Sepsis and Septic Shock

Freitas

Salomão

Tereran

et al. 2008

Clinics

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OBJECTIVES: This study aimed to assess the impact of the duration of organ dysfunction on the outcome of patients with severe sepsis or septic shock. METHODS: Clinical data were collected from hospital charts of patients with severe sepsis and septic shock admitted to a mixed intensive care unit from November 2003 to February 2004. The duration of organ dysfunction prior to diagnosis was correlated with mortality. Results were considered significant if p<0.05. RESULTS: Fifty-six patients were enrolled. Mean age was 55.6 ± 20.7 years, mean APACHE II score was 20.6 ± 6.9, and mean SOFA score was 7.9 ± 3.7. Thirty-six patients (64.3%) had septic shock. The mean duration of organ dysfunction was 1.9 ± 1.9 days. Within the univariate analysis, the variables correlated with hospital mortality were: age (p=0.015), APACHE II (p=0.008), onset outside the intensive care unit (p=0.05), blood glucose control (p=0.05) and duration of organ dysfunction (p=0.0004). In the multivariate analysis, only a duration of organ dysfunction persisting longer than 48 hours correlated with mortality (p=0.004, OR: 8.73 (2.37-32.14)), whereas the APACHE II score remained only a slightly significant factor (p=0.049, OR: 1.11 (1.00-1.23)). Patients who received therapeutic interventions within the first 48 hours after the onset of organ dysfunction exhibited lower mortality (32.1% vs. 82.1%, p=0.0001). CONCLUSIONS: These findings suggest that the diagnosis of organ dysfunction is not being made in a timely manner. The time elapsed between the onset of organ dysfunction and initiation of therapeutic intervention can be quite long, and this represents an important determinant of survival in cases of severe sepsis and septic shock

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Section: Discussionmentioning

confidence: 99%

The Impact of Duration of Organ Dysfunction on the Outcome of Patients with Severe Sepsis and Septic Shock

Freitas

Salomão

Tereran

et al. 2008

Clinics

View full text Add to dashboard Cite

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Reduced mortality after the implementation of a protocol for the early detection of severe sepsis

Westphal

Köenig

Filho

et al. 2011

Journal of Critical Care

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Comparison of Sepsis Screening Tools' Ability to Detect Sepsis Accurately

Wawrose

Baraniuk

Standiford

et al. 2016

Surgical Infections

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Despite the fact that SJSA had constant surveillance over patients' EMRs, it still detected fewer septic patients than the SSS, which was performed twice per day. The difference in sensitivities and NPVs between the two tests is of particular importance, because this indicates that the SSS is more effective in identifying patients with sepsis. This study establishes a basis for the utilization of the SSS instead of the SJSA.

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Do they know what is sepsis time? Septic Patients Survey Enrolling Staffs study

Cited by 4 publications

References 0 publications

The Impact of Duration of Organ Dysfunction on the Outcome of Patients with Severe Sepsis and Septic Shock

The Impact of Duration of Organ Dysfunction on the Outcome of Patients with Severe Sepsis and Septic Shock

Reduced mortality after the implementation of a protocol for the early detection of severe sepsis

Comparison of Sepsis Screening Tools' Ability to Detect Sepsis Accurately

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