Do we really improve life quality after total knee arthroplasty in patients with Parkinson’s disease?

Montiel, Verónica; Vitoria, María; Sola, Jose María de Espinosa Vázquez de Lamo; Nin, Juan Ramón Valentí; Azcárate, Andrés Valentí

doi:10.1007/s00402-020-03644-8

Cited by 10 publications

(14 citation statements)

References 34 publications

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“…These results indicate that patients with PD have a poorer improvement in QOL after TKA compared to patients with KOA alone, but still relieve symptoms or pain related disability. The results are not entirely consistent with the view that TKA can signi cantly improve pain in PD patients [40,41].More importantly, all of these results indicate that there was no signi cant improvement in overall QOL after TKA in the PD patient. The reason why the QOL of PD patients cannot be signi cantly improved after TKA is not clear.…”

Section: Qol In Pd Patientsmentioning

confidence: 59%

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Zong

Hao

Zhang

et al. 2022

Preprint

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Background: The number of Parkinson's patients (PD) undergoing total knee arthroplasty (TKA) is increasing. The purpose of the study was to characterize quality of life (QOL) outcomes for patients with coexisting PD and knee osteoarthritis (KOA) following TKA.Methods: Patients with coexisting PD and KOA undergoing TKA between June 2014 and June 2020 were included. These patients were matched to controls with KOA alone by age, gender, basic social background information and Knee society score（KSS）. The primary measure was to assess the QOL by the absolute changes in the EuroQOL5-Dimensions (EQ-5D), Pain and Disability Questionnaire (PDQ), and Patient Health Questionnaire-9(PHQ-9) at the last follow-up (LFU). Secondary measures were changes in QOL that exceeded the minimum clinically important difference value (MCID). Data on the health status and QOL of all patients were collected. Simple and multivariate regression analysis was used to evaluate the impact of PD on their QOL.Results: Twelve KOA patients with PD were compared with 48 controls. Control patients experienced QOL improvement across all three measures：EQ-5D index (0.545-0.717, P <0.01), PDQ (81.1-52.3, P < 0.01) and PHQ-9(8.22-5.91, P < 0.01) were significantly improved at the LFU; while in patients with PD, only PDQ (91.0-81.4, P =0.03) slightly improved. There were significant differences in the improvement of QOL between PD patients and the control group through EQ-5D (0.531 vs.0.717, P< 0.01) and PDQ (81.4vs.52.3, P <0.01) at the LFU.Conclusion: TKA has no benefit of QOL beyond a slight improvement in pain-related disability in the KOA patients with PD.

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Section: Qol In Pd Patientsmentioning

confidence: 59%

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Zong

Hao

Zhang

et al. 2022

Preprint

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“…Postoperatively, the control group showed significant improvement in all indicators, while the PD patients only showed slight improvement in PDQ. In addition, compared with the control group, postoperative QOL was significantly worse in PD patients as assessed by EQ-5D (0.531 vs.0.717, P < 0.01) and PDQ (81.4vs.52.3, The results are not entirely consistent with the view that TKA can significantly improve pain in PD patients [40,41].More importantly, all of these results indicate that there was no significant improvement in overall QOL after TKA in the PD patient. The reason why the QOL of PD patients cannot be significantly improved after TKA is not clear.…”

Section: Qol In Pd Patients After Tkamentioning

confidence: 85%

“…However, no studies have reported the improvement of QOL in PD patients after TKA. Montiel et al [41]. questioned the improvement of QOL in PD patients after TKA, but did not draw a conclusion on whether QOL was improved or not.…”

Section: Qol In Pd Patients After Tkamentioning

confidence: 99%

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Zong

Hao

Zhang

et al. 2022

BMC Musculoskelet Disord

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Background The number of Parkinson’s patients (PD) undergoing total knee arthroplasty (TKA) is increasing. The purpose of the study was to characterize quality of life (QOL) outcomes for patients with coexisting PD and knee osteoarthritis (KOA) following TKA. Methods Patients with coexisting PD and KOA undergoing TKA between June 2014 and June 2020 were included. These patients were matched to controls with KOA alone by age, gender, basic social background information and Knee society score (KSS). The primary measure was to assess the QOL by the absolute changes in the EuroQOL5-Dimensions (EQ-5D), Pain and Disability Questionnaire (PDQ), and Patient Health Questionnaire-9(PHQ-9) at the last follow-up (LFU). Secondary measures were changes in QOL that exceeded the minimum clinically important difference value (MCID). Data on the health status and QOL of all patients were collected. Simple and multivariate regression analysis was used to evaluate the impact of PD on their QOL. Results Twelve KOA patients with PD were compared with 48 controls. Control patients experienced QOL improvement across all three measures:EQ-5D index (0.545–0.717, P < 0.01), PDQ (81.1–52.3, P < 0.01) and PHQ-9(8.22–5.91, P < 0.01) were significantly improved at the LFU; while in patients with PD, only PDQ (91.0–81.4, P = 0.03) slightly improved. There were significant differences in the improvement of QOL between PD patients and the control group through EQ-5D (0.531 vs.0.717, P < 0.01) and PDQ (81.4vs.52.3, P < 0.01) at the LFU. Conclusion TKA has no benefit of QOL beyond a slight improvement in pain-related disability in the KOA patients with PD.

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“…In 2021, Montiel Terrón et al evaluated the functional outcomes achieved after TKA in patients with PD. They performed a retrospective review of 26 patients (32 knees) with PD and OA who had undergone TKA ( 11 ). The patients’ functional status was assessed with the KSFS and the KSS.…”

Section: The Impact Of Pd On Results Of Primary Tkamentioning

confidence: 99%

“…Function improved from 32 (range: 20–45) to 71 (range: 50–81) and from 34 (range: 28–52) to 59 (range: 25–76) on the KSS and KSFS, respectively. Functional outcome was related to disease progression and therefore variable ( 11 ).…”

Section: The Impact Of Pd On Results Of Primary Tkamentioning

confidence: 99%

The impact of Parkinson’s disease on results of primary total knee arthroplasty

Rodríguez-Merchán

Kalbakdij-Sánchez²

2022

EFORT Open Reviews

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Parkinson’s disease (PD) is a common neurodegenerative disorder. When patients with PD undergo total knee arthroplasty (TKA) for knee osteoarthritis, poorer knee function and poorer quality of life are obtained than in matched cohorts (MCs). However, the degree of patient satisfaction is usually high. The mean length of stay is 6.5% longer in patients with PD than in MCs. Compared with MCs, patients with PD undergoing TKA have a 44% higher risk of complications. In patients with PD, the overall complication rate is 26.3% compared with 10.5% in MCs; the periprosthetic joint infection rate is 6.5% in patients with PD vs 1.7% in MCs; and the periprosthetic fracture rate is 2.1% in patients with PD vs 1.7% in MCs. The 90-day readmission rate is 16.29% in patients with PD vs 12.66% in MCs. More flexion contractures occur in patients with PD. The rate of medical complications is 4.21% in patients with PD vs 1.24% in MCs, and the rate of implant-related complications is 5.09% in patients with PD vs 3.15% in MCs. At 5.3 years’ mean follow-up, the need for revision surgery is 23.6%. The 10-year implant survival, taking revision of any of the components as an endpoint, is 89.7% in patients with PD vs 98.3% in MCs.

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Do we really improve life quality after total knee arthroplasty in patients with Parkinson’s disease?

Cited by 10 publications

References 34 publications

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

Quality of life assessment after total knee arthroplasty in patients with Parkinson’s disease

The impact of Parkinson’s disease on results of primary total knee arthroplasty

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