Do we really need to reconsider coligranulomatosis (Hjärre and Wramby’s disease) in poultry?

Liebhart, Dieter; Heß, Michael

doi:10.1080/03079457.2017.1414149

Cited by 2 publications

(3 citation statements)

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“…Because in other studies in poultry, it has been reported that necrotic lesions and granulomas due to Tetratrichomonas gallinarum have been diagnosed by showing them with histological and special staining (Liebhart and Hess, 2018;Liebhart et al, 2014;Patton and Patton, 1996;Richter et al, 2010). In our study, the presence of this agent could not be confirmed as a result of staining with H.E., Giemsa, or PAS method and as a result of parasitological examinations.…”

Section: Discussioncontrasting

confidence: 65%

“…They saw this as the reason that past cases were not coligranulomatosis (Landman and van Eck, 2017). There are opposite views, like ours, that the etiology of coligranulomatosis does not need to be re-considered in poultry (Liebhart and Hess, 2018). This is because normal healthy poultry has been reported to be highly resistant to virulent E. coli strains (Nolan et al, 2020).…”

Section: Discussionmentioning

confidence: 64%

“…Despite this, and based on the Koch postulate, it was stated that these granulomas were originated by Tetratrichomonas gallinarum, although it was not shown in the lesions . However, this study has been criticized for this aspect (Liebhart and Hess, 2018).…”

Section: Discussionmentioning

confidence: 94%

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Pathological and Immunohistochemical Examinations on Co-Infection with Coligranulomatosis and Marek's Disease in a Turkey Flock

Ateş

Çelik

Çiftçi

2020

Tavukçuluk Araştırma Dergisi

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Coligranulomatosis, which induces hepatic granulomas, and Marek's disease, one of the important neoplastic diseases in poultry, rarely causes outbreaks in turkeys. In this study, etiological diagnoses were performed in the light of post-mortem, histopathological, microbiological, and immunohistochemistry studies of turkeys that died in a commercial establishment in the region of Konya. In the post-mortem examination, many grey-white foci with a diameter of 3-10 mm, which sometimes spread from serosa to the parenchyma, were found in the liver. Mucous exudate and hyperemia were detected in all segments of the intestine. For microscopic examination, all tissues were stained with Haematoxylin-Eosin and some selected liver tissues with Periodic Acid-Schiff, Ziehl-Neelsen, and Giemsa. Typical structures of pyogranulomas with an eosinophilic necrotic core in the liver were identified. Tumor foci formed by pleomorphic histiocyte and lymphoid cells were also observed in the liver, spleen, and intestines (jejunum and cecum). In the selected liver and intestinal sections, a positive reaction was obtained in tumor cells in immunohistochemical staining with the primary antibody specific for Marek's disease virus. In addition, Escherichia coli isolation was performed microbiologically in swaps and samples taken from lesioned areas of the liver. As a result of the examinations, other etiological agents that may cause hepatic granulomas in the turkeys were excluded, and coligranulomatosis and Marek's disease were diagnosed simultaneously in this turkey flock. It was concluded that in cases in which these two diseases are observed simultaneously, the diseases might interact with each other, and casualties may increase.

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Section: Discussioncontrasting

confidence: 65%

Section: Discussionmentioning

confidence: 64%