Background: Schema therapy (ST) is a proven effective treatment in chronic psychopathology and has thus become a popular transdiagnostic treatment approach among practitioners in recent times. Nonetheless, ST is not free of theoretical criticisms, research gaps, and practical challenges. As a complex model with a multiplicity of components and subcomponents, ST can be challenging for therapists to learn, and for clients to use. Purpose: To present the Sherlock Holmes metaphor as a highly suitable therapist-generated enactive or embodied metaphor to explain to clients four key components and tasks: the therapeutic alliance; case conceptualization; the practice of mindfulness; and the role, functionality, and embodiment of the Healthy Adult (HA) mode. Method: Qualitative-literature review and vignette examples, using interpretative phenomenological analysis. Results: The psychological linkages between theory and practice are elucidated, and the therapeutic factors and mechanisms of change embedded in the use of enactive/embodied metaphor are unpacked. Conclusion: The Sherlock Holmes metaphor is an image schema that offers clients a vivid, powerful, and memorable anchor they can use to evoke and enact their HA mode, as a positive psychological intervention to achieve their goals. For psychotherapists, the Sherlock Holmes metaphor represents a parsimonious, creative, and flexible device, aligned with the integrative psychotherapy tradition, which they can blend into their own style and practice. The paper contributes to the multiple nuances of ST, responds to calls to understand the dynamics and signification of metaphor as action in psychotherapy, and illustrates how imagination supports the mental ability to respond to fictional characters.