2020
DOI: 10.1016/j.eplepsyres.2019.106260
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Do women with epilepsy benefit from epilepsy specific pre-conception care?

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Cited by 11 publications
(3 citation statements)
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“…For women with epilepsy who hope to conceive, many worry about how seizures, epilepsy treatment, and their developing fetus will impact one another. Preconception counseling, in addition to addressing women’s concerns, has been prospectively observed to lower antiseizure medication burden, improve folic acid use, and reduce seizure burden 40 . The value of preconception counseling is reinforced by its role in ensuring informed consent when choosing epilepsy therapies.…”
Section: Preconception Counselingmentioning
confidence: 99%
“…For women with epilepsy who hope to conceive, many worry about how seizures, epilepsy treatment, and their developing fetus will impact one another. Preconception counseling, in addition to addressing women’s concerns, has been prospectively observed to lower antiseizure medication burden, improve folic acid use, and reduce seizure burden 40 . The value of preconception counseling is reinforced by its role in ensuring informed consent when choosing epilepsy therapies.…”
Section: Preconception Counselingmentioning
confidence: 99%
“…According to studies published in the past decade, preconceptional FA supplementation rates in women of childbearing age with epilepsy, including adolescent women, range between 9% and 52% (Hao et al, 2015; Herzog et al, 2017; Ishikawa et al, 2020; Minshall & Neligan, 2014; Moura et al, 2015; Passarelli et al, 2015; Petersen et al, 2019). Higher rates (82% and 88%) were reported with preconception care and following interventions that increased physician and patient awareness of the guidelines, adherence to pregnancy counseling during outpatient visits, and electronic reminders of FA prescription in women of childbearing age with epilepsy on AEDs (Baishya et al, 2020; Keni et al, 2020; Patel et al, 2018). Low FA supplementation rates were related to low rates of pregnancy counseling and FA prescription nonadherence, and were associated with specific clinical and demographic variables such as planned pregnancy, contraceptive method, education level, race, income, employment, and area of living (urban vs. rural in a developing country) (Herzog et al, 2017; Ishikawa et al, 2020; Minshall & Neligan, 2014; Moura et al, 2015; Passarelli et al, 2015).…”
Section: Discussionmentioning
confidence: 99%
“…It is well established that most pregnancies in women with or without epilepsy are not planned. Preconceptional care has shown to improve seizure control during pregnancy and increase folic acid intake 12 ; however, it has not shown to decrease the risk for MFM, bringing back the argument that the rate of MFM in WWE is likely more related to the choice of ASM than the use of folic acid, in contrast to the general population. The possibility of folic acid improving long-term cognitive outcome in children born to WWE strengthens the case for the recommendation to take folic acid at a dose between 0.4 and 4 mg a day in the periconceptional period and throughout the pregnancy.…”
Section: Commentarymentioning
confidence: 99%