Do women with primary breast cancer who experience chemotherapy-induced menopause have worse symptoms than those due to natural menopause?

Tchen, N.; Fan, Hongwei; Yi, Qilong; Chemerynsky, I.; Galica, Jacqueline; Sabate, K.; Tannock, Ian F.

doi:10.1200/jco.2005.23.16_suppl.8016

Cited by 2 publications

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“…The only long-term trial investigating the efficacy of citalopram and fluoxetine (two antidepressants) in a 9-month placebo-controlled trial did not find any difference between the three treatment arms, even on increasing the dose after 6 months [21]. This might be explained by the different characteristics and severity of menopausal symptoms in cancer and noncancer patients [22].…”

Section: Discussionmentioning

confidence: 80%

Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients—a double-blind, randomized study

et al. 2007

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Background: Classical hormone replacement therapy for hot flashes is contraindicated in breast cancer especially in endocrine responsive disease. Patients and methods:In a double-blind, randomized phase III study, breast cancer patients suffering from hot flashes at least twice a day, who were not taking any medication against hypertension and depression received either clonidine 0.075 mg twice a day or venlafaxine 37.5 mg twice a day for 4 weeks. The primary end point was defined as the frequency of hot flashes after 4 weeks of treatment. A self-reported 1-week hot flash and other symptom questionnaire were kept before the start of treatment until the end of treatment course. Conclusion:Venlafaxine is significantly more effective in reducing the frequency of hot flashes in breast cancer patients than clonidine.

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Section: Discussionmentioning

confidence: 80%

Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients—a double-blind, randomized study

et al. 2007

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Chemotherapy-Induced Premature Menopause Among Latina Women With Breast Cancer: An Interpretive Description: A Dissertation

Brisbois¹

2013

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Do women with primary breast cancer who experience chemotherapy-induced menopause have worse symptoms than those due to natural menopause?

Cited by 2 publications

References 0 publications

Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients—a double-blind, randomized study

Venlafaxine is superior to clonidine as treatment of hot flashes in breast cancer patients—a double-blind, randomized study

Chemotherapy-Induced Premature Menopause Among Latina Women With Breast Cancer: An Interpretive Description: A Dissertation

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